ID   Y149_TREPA              Reviewed;         197 AA.
AC   O83184;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Uncharacterized protein TP_0149;
GN   OrderedLocusNames=TP_0149;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65141.1; -; Genomic_DNA.
DR   PIR; F71361; F71361.
DR   RefSeq; WP_010881596.1; NC_021490.2.
DR   AlphaFoldDB; O83184; -.
DR   IntAct; O83184; 2.
DR   STRING; 243276.TPANIC_0149; -.
DR   EnsemblBacteria; AAC65141; AAC65141; TP_0149.
DR   KEGG; tpa:TP_0149; -.
DR   eggNOG; ENOG5032I09; Bacteria.
DR   HOGENOM; CLU_1377595_0_0_12; -.
DR   OMA; REFFAFG; -.
DR   OrthoDB; 1834273at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..197
FT                   /note="Uncharacterized protein TP_0149"
FT                   /id="PRO_0000202201"
FT   TRANSMEM        12..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   197 AA;  21542 MW;  B4EE40FD4BE9BD81 CRC64;
     MSKYTVKRAS VLCIFGIGLF VPATGTFACG LLLVLGFWVL FFSSLLARFL SQFFMRTRSA
     PLFEVCLTLS ATIMYDNLIQ GFFPLVRMML CPYLFITALS RTLDLCLTAY DADAESLECV
     GVFGIMIAGI SLVRELVAFG CVSLPAPSGF LRIISFPPSN VIRFAATGAG TLISCGIVLW
     IFRSAGNDHT PSLRSEW