ID   Y1503_SHEFN             Reviewed;         291 AA.
AC   O33730; Q084G1;
DT   17-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Uncharacterized oxidoreductase Sfri_1503;
DE            EC=1.1.-.-;
GN   OrderedLocusNames=Sfri_1503;
OS   Shewanella frigidimarina (strain NCIMB 400).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=318167;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCIMB 400;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Fredrickson J.K., Kolker E., McCuel L.A., DiChristina T., Nealson K.H.,
RA   Newman D., Tiedje J.M., Zhou J., Romine M.F., Culley D.E., Serres M.,
RA   Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.;
RT   "Complete sequence of Shewanella frigidimarina NCIMB 400.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 97-291.
RX   PubMed=10861223; DOI=10.1042/0264-6021:3490153;
RA   Gordon E.H.J., Pike A.D., Hill A.E., Cuthbertson P.M., Chapman S.K.,
RA   Reid G.A.;
RT   "Identification and characterization of a novel cytochrome c3 from
RT   Shewanella frigidimarina that is involved in Fe(III) respiration.";
RL   Biochem. J. 349:153-158(2000).
CC   -!- SIMILARITY: Belongs to the HIBADH-related family. {ECO:0000305}.
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DR   EMBL; CP000447; ABI71354.1; -; Genomic_DNA.
DR   EMBL; AJ000006; CAA03849.1; -; Genomic_DNA.
DR   RefSeq; WP_011636974.1; NC_008345.1.
DR   AlphaFoldDB; O33730; -.
DR   SMR; O33730; -.
DR   STRING; 318167.Sfri_1503; -.
DR   EnsemblBacteria; ABI71354; ABI71354; Sfri_1503.
DR   KEGG; sfr:Sfri_1503; -.
DR   eggNOG; COG2084; Bacteria.
DR   HOGENOM; CLU_035117_1_0_6; -.
DR   OMA; IFVDHTT; -.
DR   OrthoDB; 1194694at2; -.
DR   Proteomes; UP000000684; Chromosome.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR029154; NADP-bd.
DR   Pfam; PF14833; NAD_binding_11; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE   3: Inferred from homology;
KW   NAD; Oxidoreductase; Reference proteome.
FT   CHAIN           1..291
FT                   /note="Uncharacterized oxidoreductase Sfri_1503"
FT                   /id="PRO_0000173071"
FT   ACT_SITE        172
FT                   /evidence="ECO:0000250"
FT   BINDING         5..19
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   BINDING         97
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   BINDING         240
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        157
FT                   /note="Missing (in Ref. 2; CAA03849)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        211
FT                   /note="A -> R (in Ref. 2; CAA03849)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   291 AA;  31116 MW;  ED991E40A4838982 CRC64;
     MAKVAFIGLG VMGFPMAGHL VKQGHDVTVY NRTGAKATQW VEQYGGKKAD TPKDAAQGQD
     IVFTCVGNDD DLRQVVLGEH GIVHGMHAGA ILVDHTTASA DVAREIAAYI EPLNIAFLDA
     PVSGGQAGAE NGALTVMMGG DQAHFDTVKP VISAYSRCAE LLGPVGAGQL TKMVNQICIA
     GVVQGLAEGL HFAKSAGLDG LKVIEVISKG AAQSWQMENR YKTMWQGQYD FGFAIDWMRK
     DLGIALDEAR RNGSHLPVAA LVDQFYSEVQ AMKGNRWDTS SLLARLEKSR S