ID   Y1511_STRP8             Reviewed;         279 AA.
AC   P67373; Q99YY0;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=DegV domain-containing protein spyM18_1511;
GN   OrderedLocusNames=spyM18_1511;
OS   Streptococcus pyogenes serotype M18 (strain MGAS8232).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=186103;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGAS8232;
RX   PubMed=11917108; DOI=10.1073/pnas.062526099;
RA   Smoot J.C., Barbian K.D., Van Gompel J.J., Smoot L.M., Chaussee M.S.,
RA   Sylva G.L., Sturdevant D.E., Ricklefs S.M., Porcella S.F., Parkins L.D.,
RA   Beres S.B., Campbell D.S., Smith T.M., Zhang Q., Kapur V., Daly J.A.,
RA   Veasy L.G., Musser J.M.;
RT   "Genome sequence and comparative microarray analysis of serotype M18 group
RT   A Streptococcus strains associated with acute rheumatic fever outbreaks.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4668-4673(2002).
CC   -!- FUNCTION: May bind long-chain fatty acids, such as palmitate, and may
CC       play a role in lipid transport or fatty acid metabolism. {ECO:0000250}.
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DR   EMBL; AE009949; AAL98082.1; -; Genomic_DNA.
DR   AlphaFoldDB; P67373; -.
DR   SMR; P67373; -.
DR   KEGG; spm:spyM18_1511; -.
DR   HOGENOM; CLU_048251_3_2_9; -.
DR   OMA; EIHAKIN; -.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1180.10; -; 1.
DR   InterPro; IPR003797; DegV.
DR   InterPro; IPR043168; DegV_C.
DR   Pfam; PF02645; DegV; 1.
DR   TIGRFAMs; TIGR00762; DegV; 1.
DR   PROSITE; PS51482; DEGV; 1.
PE   3: Inferred from homology;
KW   Lipid-binding.
FT   CHAIN           1..279
FT                   /note="DegV domain-containing protein spyM18_1511"
FT                   /id="PRO_0000209807"
FT   DOMAIN          4..278
FT                   /note="DegV"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00815"
FT   BINDING         62
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT   BINDING         95
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
SQ   SEQUENCE   279 AA;  29952 MW;  9DADBF96BD822A0D CRC64;
     MGTIKIVTDS SITIEPELIK ALDITVVPLS VMIDSKLYSD NDLKEEGHFL SLMKASKSLP
     KTSQPPVGLF AETYENLVKK GVTDIVAIHL SPALSGTIEA SRQGAEIAEA PVTVLDSGFT
     DQAMKFQVVE AAKMAKAGAS LNEILAAVQA IKSKTELYIG VSTLENLVKG GRIGRVTGVL
     SSLLNVKVVM ALKNDELKTL VKGRGNKTFT KWLDSYLAKN SHRPIAEIAI SYAGEASLAL
     TLKERIAAYY NHSISVLETG SIIQTHTGEG AFAVMVRYE