Y1514_ARATH
ID Y1514_ARATH Reviewed; 617 AA.
AC Q9FRK5; Q8GY41; Q9C9Q7;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 3.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=Uncharacterized membrane protein At1g75140;
GN OrderedLocusNames=At1g75140; ORFNames=22H5.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG51915.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC013258; AAG51915.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC025814; AAG12694.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35676.1; -; Genomic_DNA.
DR EMBL; AK117881; BAC42521.1; -; mRNA.
DR EMBL; BT005930; AAO64865.1; -; mRNA.
DR PIR; E96781; E96781.
DR RefSeq; NP_177650.1; NM_106170.5.
DR AlphaFoldDB; Q9FRK5; -.
DR SMR; Q9FRK5; -.
DR BioGRID; 29070; 3.
DR IntAct; Q9FRK5; 3.
DR iPTMnet; Q9FRK5; -.
DR PaxDb; Q9FRK5; -.
DR PRIDE; Q9FRK5; -.
DR ProteomicsDB; 242420; -.
DR EnsemblPlants; AT1G75140.1; AT1G75140.1; AT1G75140.
DR GeneID; 843851; -.
DR Gramene; AT1G75140.1; AT1G75140.1; AT1G75140.
DR KEGG; ath:AT1G75140; -.
DR Araport; AT1G75140; -.
DR TAIR; locus:2025157; AT1G75140.
DR eggNOG; ENOG502QQN0; Eukaryota.
DR HOGENOM; CLU_027388_0_0_1; -.
DR InParanoid; Q9FRK5; -.
DR OMA; MSVRETP; -.
DR OrthoDB; 499799at2759; -.
DR PRO; PR:Q9FRK5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FRK5; baseline and differential.
DR Genevisible; Q9FRK5; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR InterPro; IPR045288; At1g75140-like.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR35464; PTHR35464; 1.
DR SUPFAM; SSF50978; SSF50978; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..617
FT /note="Uncharacterized membrane protein At1g75140"
FT /id="PRO_0000300107"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 473..493
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 34..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 511..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 60..86
FT /evidence="ECO:0000255"
FT COMPBIAS 511..530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..545
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..585
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 330
FT /note="A -> T (in Ref. 3; BAC42521 and 4; AAO64865)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 617 AA; 68909 MW; CE259912CAAD7B78 CRC64;
MADSQNGKSA FFFFFVSLIL LFLSPSYSDV TASESDPIPY ENSDASPGVV TSSESDRQGV
SLHRLEELVR NLTELVARLD AKLSETPFKV KKEITRDEIE EKAKAFSVTK YSPFWSERFE
FTSAVKLDSE ATCINVLPFR DHEGLSKYFA VGDSSGRVFV FLRNGDVLVE FFTTCDSPIT
AMVSYMSVYK NESFVVTGHQ SGVILLHRLR EGSIGEDLNS AVMENVGKFD GTEDGLQVTL
LEVHHVGRVR YILATDLSGK LTVFTENRTV YGSVSPTSRP LVFLKQRLLF LTETGAGSLD
LRSMKIRESE CEGLNHSLAR SYVFDASERA KAYGFTSEGE IIHVLLLGDI MNFKCRVRSK
KKVQMEEPVA LQAIKGYLLI VNQEKVFVYN VSTQHYVRTT GPRLLFPAAL EDIRSTFLSH
RESTKTTDHQ KLEKVTPLIA SDREKLLVMG LGDGYVATYK SKLPISKAEF NTMLWSSPVF
FFILFLFGAW HFFSKKKESL TAWGPDDPFS STTMSSSSTT TAQNSSAFSE STRRNDDHMD
LRRRYVSPSR YPPGAATGAY RSVGSNDPSS RAPVETTNYR TTAQEMKYRG GSGLDSGGFG
KRRESLFGNN KALDDES
