Y1517_MYCBO
ID Y1517_MYCBO Reviewed; 335 AA.
AC P64856; A0A1R3XYH9; P71762; X2BII7;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=UPF0353 protein Mb1517 {ECO:0000255|HAMAP-Rule:MF_01340};
GN OrderedLocusNames=BQ2027_MB1517;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01340};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01340}.
CC -!- SIMILARITY: Belongs to the UPF0353 family. {ECO:0000255|HAMAP-
CC Rule:MF_01340}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LT708304; SIU00120.1; -; Genomic_DNA.
DR RefSeq; NP_855169.1; NC_002945.3.
DR RefSeq; WP_003407530.1; NC_002945.4.
DR AlphaFoldDB; P64856; -.
DR SMR; P64856; -.
DR EnsemblBacteria; SIU00120; SIU00120; BQ2027_MB1517.
DR GeneID; 45425460; -.
DR PATRIC; fig|233413.5.peg.1658; -.
DR OMA; RYFRATD; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.410; -; 1.
DR HAMAP; MF_01340; UPF0353; 1.
DR InterPro; IPR022933; UPF0353.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; SSF53300; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..335
FT /note="UPF0353 protein Mb1517"
FT /id="PRO_0000057643"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT TRANSMEM 309..329
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT DOMAIN 98..294
FT /note="VWFA"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
SQ SEQUENCE 335 AA; 36030 MW; A8562F98A30DA86C CRC64;
MTLPLLGPMT LSGFAHSWFF LFLFVVAGLV ALYILMQLAR QRRMLRFANM ELLESVAPKR
PSRWRHVPAI LLVLSLLLFT IAMAGPTHDV RIPRNRAVVM LVIDVSQSMR ATDVEPSRMV
AAQEAAKQFA DELTPGINLG LIAYAGTATV LVSPTTNREA TKNALDKLQF ADRTATGEAI
FTALQAIATV GAVIGGGDTP PPARIVLFSD GKETMPTNPD NPKGAYTAAR TAKDQGVPIS
TISFGTPYGF VEINDQRQPV PVDDETMKKV AQLSGGNSYN AATLAELRAV YSSLQQQIGY
ETIKGDASVG WLRLGALALA LAALAALLIN RRLPT