ID   Y1518_MYCBT             Reviewed;         335 AA.
AC   C1ANC7;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=UPF0353 protein JTY_1518 {ECO:0000255|HAMAP-Rule:MF_01340};
GN   OrderedLocusNames=JTY_1518;
OS   Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=561275;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCG / Tokyo 172 / ATCC 35737 / TMC 1019;
RX   PubMed=19200449; DOI=10.1016/j.vaccine.2009.01.034;
RA   Seki M., Honda I., Fujita I., Yano I., Yamamoto S., Koyama A.;
RT   "Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-
RT   Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains.";
RL   Vaccine 27:1710-1716(2009).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01340};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01340}.
CC   -!- SIMILARITY: Belongs to the UPF0353 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01340}.
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DR   EMBL; AP010918; BAH25806.1; -; Genomic_DNA.
DR   RefSeq; WP_011799186.1; NZ_CP014566.1.
DR   AlphaFoldDB; C1ANC7; -.
DR   SMR; C1ANC7; -.
DR   KEGG; mbt:JTY_1518; -.
DR   HOGENOM; CLU_024570_2_0_11; -.
DR   OMA; RYFRATD; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.410; -; 1.
DR   HAMAP; MF_01340; UPF0353; 1.
DR   InterPro; IPR022933; UPF0353.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..335
FT                   /note="UPF0353 protein JTY_1518"
FT                   /id="PRO_1000166265"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   DOMAIN          98..294
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
SQ   SEQUENCE   335 AA;  36031 MW;  A85B4F95CE6DA50C CRC64;
     MTLPLLGPMT LSGFAHSWFF LFLFVVAGLV ALYILMQLAR QRRMLRFANM ELLESVAPKR
     PSRWRHVPAI LLVLSLLLFT IAMAGPTHDV RIPRNRAVVM LVIDVSQSMR ATDVEPSRMV
     AAQEAAKQFA DELTPGINLG LIAYAGTATV LVSPTTNREA TKNALDKLQF ADRTATGEAI
     FTALQAIATV GAVIGGGDTP PPARIVLFSD GKETMPTNPD NPKGAYTAAR TAKDQGVPIS
     TISFGTPYGF VEIDDQRQPV PVDDETMKKV AQLSGGNSYN AATLAELRAV YSSLQQQIGY
     ETIKGDASVG WLRLGALALA LAALAALLIN RRLPT