ID   Y1527_STAES             Reviewed;         376 AA.
AC   Q8CRX9;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=UPF0754 membrane protein SE_1527;
GN   OrderedLocusNames=SE_1527;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0754 family. {ECO:0000305}.
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DR   EMBL; AE015929; AAO05126.1; -; Genomic_DNA.
DR   RefSeq; NP_765082.1; NC_004461.1.
DR   RefSeq; WP_011082738.1; NZ_WBME01000024.1.
DR   AlphaFoldDB; Q8CRX9; -.
DR   STRING; 176280.SE_1527; -.
DR   DNASU; 1055800; -.
DR   EnsemblBacteria; AAO05126; AAO05126; SE_1527.
DR   KEGG; sep:SE_1527; -.
DR   PATRIC; fig|176280.10.peg.1492; -.
DR   eggNOG; COG4399; Bacteria.
DR   HOGENOM; CLU_042384_0_0_9; -.
DR   OMA; DTIMGSL; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007383; DUF445.
DR   InterPro; IPR016991; UCP032178.
DR   Pfam; PF04286; DUF445; 1.
DR   PIRSF; PIRSF032178; UCP032178; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..376
FT                   /note="UPF0754 membrane protein SE_1527"
FT                   /id="PRO_0000388319"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   376 AA;  44347 MW;  936A508F3DC4124C CRC64;
     MHTILLVVFM IILGAIIGGV TNMIAIKMLF HPFKPYYIFR FRIPFTPGLI PKRREEIARK
     IGQVIEEHLI TEELIRQKLN QPQSRNMIQQ LIHKQISKLK NDDVTIKKIA GFLGIDVNEL
     VDYKLTTKFL NKLNFWYESN KYRKLSEILP QSFLDQCKGQ IEYITDFLCE RARNYLSSEK
     GERDIYEMLD TFFNEKGRII GLLQMFMTKE SIADRIQHEL IRLTQHPQSQ KIITKVLNDE
     YEIFKDKNLD EIIKEQQFKN YSQLVLNELK TYLNLKDKTE RPIKQVVPQF IQFLEDDTSK
     RMTDFIIKGT SKHLTNIMKK INLRQLVEEQ INTFDLKYIE NLIIDIANKE LKLIMTLGFI
     LGGIIGFFQG VIAIFV