Y1530_STAAN
ID Y1530_STAAN Reviewed; 351 AA.
AC Q7A552;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 2.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Uncharacterized peptidase SA1530;
DE EC=3.4.-.-;
GN OrderedLocusNames=SA1530;
OS Staphylococcus aureus (strain N315).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=158879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N315;
RX PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA Hiramatsu K.;
RT "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL Lancet 357:1225-1240(2001).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=N315;
RA Vaezzadeh A.R., Deshusses J., Lescuyer P., Hochstrasser D.F.;
RT "Shotgun proteomic analysis of total and membrane protein extracts of S.
RT aureus strain N315.";
RL Submitted (OCT-2007) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000305};
CC Note=Binds 2 manganese ions per subunit. {ECO:0000305};
CC -!- SIMILARITY: Belongs to the peptidase M24B family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB42797.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; BA000018; BAB42797.1; ALT_INIT; Genomic_DNA.
DR PIR; H89954; H89954.
DR RefSeq; WP_000161666.1; NC_002745.2.
DR AlphaFoldDB; Q7A552; -.
DR SMR; Q7A552; -.
DR EnsemblBacteria; BAB42797; BAB42797; BAB42797.
DR KEGG; sau:SA1530; -.
DR HOGENOM; CLU_017266_4_2_9; -.
DR Proteomes; UP000000751; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.350.10; -; 1.
DR Gene3D; 3.90.230.10; -; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF53092; SSF53092; 1.
DR SUPFAM; SSF55920; SSF55920; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 1: Evidence at protein level;
KW Hydrolase; Manganese; Metal-binding.
FT CHAIN 1..351
FT /note="Uncharacterized peptidase SA1530"
FT /id="PRO_0000299424"
FT BINDING 215
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 226
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 226
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 290
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 319
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 333
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 333
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
SQ SEQUENCE 351 AA; 39607 MW; FF1EDFC587663663 CRC64;
MTKISKIIDE LNNQQADAAW ITTPLNVYYF TGYRSEPHER LFALLIKKDG KQVLFCPKME
VEEVKASPFT GEIVGYLDTE NPFSLYPQTI NKLLIESEHL TVARQKQLIS GFNVNSFGDV
DLTIKQLRNI KSEDEISKIR KAAELADKCI EIGVSYLKEG VTEREVVNHI EQTIKQYGVN
EMSFDTMVLF GDHAASPHGT PGDRRLKSNE YVLFDLGVIY EHYCSDMTRT IKFGEPSKEA
QEIYNIVLEA ETSAIQAIKP GIPLKDIDHI ARNIISEKGY GEYFPHRLGH GLGLQEHEYQ
DVSSTNSNLL EAGMVITIEP GIYVPGVAGV RIEDDILVTN EGYEVLTHYE K