Y1533_ARCFU
ID Y1533_ARCFU Reviewed; 278 AA.
AC O28739;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Uncharacterized transporter AF_1533;
GN OrderedLocusNames=AF_1533;
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE000782; AAB89716.1; -; Genomic_DNA.
DR PIR; D69441; D69441.
DR RefSeq; WP_010879030.1; NC_000917.1.
DR AlphaFoldDB; O28739; -.
DR SMR; O28739; -.
DR STRING; 224325.AF_1533; -.
DR TCDB; 2.A.7.3.5; the drug/metabolite transporter (dmt) superfamily.
DR EnsemblBacteria; AAB89716; AAB89716; AF_1533.
DR GeneID; 1484761; -.
DR KEGG; afu:AF_1533; -.
DR eggNOG; arCOG00272; Archaea.
DR HOGENOM; CLU_082650_1_0_2; -.
DR OMA; WAILWAY; -.
DR OrthoDB; 62718at2157; -.
DR PhylomeDB; O28739; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR000620; EamA_dom.
DR Pfam; PF00892; EamA; 2.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..278
FT /note="Uncharacterized transporter AF_1533"
FT /id="PRO_0000108204"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 170..190
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 230..250
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 12..136
FT /note="EamA 1"
FT DOMAIN 154..274
FT /note="EamA 2"
SQ SEQUENCE 278 AA; 30446 MW; EC67474A6F3A9431 CRC64;
MLEILMSLTA AICWAFNGIA YRKGVKDVSA FTANFHRTLF ATVYFLPLAL RDFPGVVIDL
QTALVLVISA MLSFYIGDLS YFASLKRSPV SIALPASSTY PVYVVLLSTV IYGAELSLNA
LISAILVFVA VYIIYGSGEK GETSGLFYAL LAAFSWALAI LTLDFLTDRL PVSIVAFVRL
LLCLILLSFT AKKDELSTEI RLFFRSVRGI FLLLGIMLFI TAIKVSSSWN VVQPSSTSPV
FAAIFGAIFL KERISFRLVA GIFVIILAIL LLLLPPLQ
