Y1533_METJA
ID Y1533_METJA Reviewed; 642 AA.
AC Q58928;
DT 29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Uncharacterized KH and PIN-domain containing protein MJ1533;
GN OrderedLocusNames=MJ1533;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (2.64 ANGSTROMS) OF 27-165.
RG Midwest center for structural genomics (MCSG);
RT "A domain of a functionally unknown protein from Methanocaldococcus
RT jannaschii DSM 2661.";
RL Submitted (JUL-2009) to the PDB data bank.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000305};
CC -!- SIMILARITY: In the N-terminal section; belongs to the PINc/VapC protein
CC family. {ECO:0000305}.
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DR EMBL; L77117; AAB99554.1; -; Genomic_DNA.
DR PIR; D64491; D64491.
DR PDB; 3I8O; X-ray; 2.64 A; A=27-165.
DR PDBsum; 3I8O; -.
DR AlphaFoldDB; Q58928; -.
DR SMR; Q58928; -.
DR STRING; 243232.MJ_1533; -.
DR PRIDE; Q58928; -.
DR DNASU; 1452441; -.
DR EnsemblBacteria; AAB99554; AAB99554; MJ_1533.
DR KEGG; mja:MJ_1533; -.
DR eggNOG; arCOG04116; Archaea.
DR HOGENOM; CLU_023387_0_0_2; -.
DR InParanoid; Q58928; -.
DR OMA; FADMRMA; -.
DR PhylomeDB; Q58928; -.
DR EvolutionaryTrace; Q58928; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1370.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR009019; KH_sf_prok-type.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR InterPro; IPR001482; T2SS/T4SS.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF01850; PIN; 1.
DR Pfam; PF00437; T2SSE; 1.
DR SMART; SM00322; KH; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF54814; SSF54814; 1.
DR SUPFAM; SSF88723; SSF88723; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Magnesium; Metal-binding; Reference proteome; RNA-binding.
FT CHAIN 1..642
FT /note="Uncharacterized KH and PIN-domain containing protein
FT MJ1533"
FT /id="PRO_0000050166"
FT DOMAIN 29..149
FT /note="PINc"
FT DOMAIN 510..578
FT /note="KH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT BINDING 15
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000255"
FT BINDING 118
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000255"
FT STRAND 28..31
FT /evidence="ECO:0007829|PDB:3I8O"
FT HELIX 33..37
FT /evidence="ECO:0007829|PDB:3I8O"
FT HELIX 40..46
FT /evidence="ECO:0007829|PDB:3I8O"
FT TURN 47..52
FT /evidence="ECO:0007829|PDB:3I8O"
FT STRAND 54..58
FT /evidence="ECO:0007829|PDB:3I8O"
FT HELIX 59..69
FT /evidence="ECO:0007829|PDB:3I8O"
FT TURN 70..72
FT /evidence="ECO:0007829|PDB:3I8O"
FT HELIX 74..92
FT /evidence="ECO:0007829|PDB:3I8O"
FT STRAND 97..101
FT /evidence="ECO:0007829|PDB:3I8O"
FT HELIX 106..110
FT /evidence="ECO:0007829|PDB:3I8O"
FT STRAND 114..116
FT /evidence="ECO:0007829|PDB:3I8O"
FT HELIX 117..127
FT /evidence="ECO:0007829|PDB:3I8O"
FT STRAND 131..135
FT /evidence="ECO:0007829|PDB:3I8O"
FT HELIX 137..145
FT /evidence="ECO:0007829|PDB:3I8O"
FT STRAND 150..152
FT /evidence="ECO:0007829|PDB:3I8O"
SQ SEQUENCE 642 AA; 72907 MW; 9CA730BFA10ABE69 CRC64;
MKVTFMNLEE RKKLETKSID ELDLIGKKVC VDTCVVIDGR ITELIERGKL KDATIIIPEA
VVSELEYQAN MGREIGYKGI EELRKLIEKA SEHNIKVEYY GERPTREEIF LAKSGEIDAM
IRKVAKETNS ILLTSDWIQY NLAKAQGIEA YFLEAAEEEV ELVLDKYFDE ETMSVHLKEG
CLPYAKKGKP GEVKLVPIGD KELTKEEMED IIDNIIKYAE QNNGFFEIQR KGATVIQLGN
IRISIARPPF SEALEVTAVR PVVKASLEDY ELSDKLMERL KERAEGIFVS GPPGSGKSTF
VAALAEFYRS QGKIVKTMES PRDLQVSKEI TQYAPLEGDM EKTCDILLLV RPDYTIYDEV
RKTRDFEIFA DMRMAGVGMV GVVHASKPID AIQRLIGRVE LGVIPQVVDT VIFIKDGKIQ
KVYEIDFTVK VPYGMVEEDL ARPVIEVKDF ETGRVEYEIY TYGEQVVVMP IKEEGGKKAP
IYGYAEEKLE EILKKLLPRK AKPMVKVTGD NSIDLIVPEK YIGAIIGKGG KEISKLEDML
GLKISVKEKE KEEEKDMERI YRKYEYVNEL ESTRIYETDK YVVVDVGEDF AGENIRIYID
GKLLTTVTVR NDGTVRINKK TKVGKEILEA IDEGRDIYVD LQ
