ID   Y1552_ARCFU             Reviewed;         270 AA.
AC   O28720;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Uncharacterized transporter AF_1552;
GN   OrderedLocusNames=AF_1552;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR   EMBL; AE000782; AAB89694.1; -; Genomic_DNA.
DR   PIR; G69443; G69443.
DR   AlphaFoldDB; O28720; -.
DR   SMR; O28720; -.
DR   STRING; 224325.AF_1552; -.
DR   EnsemblBacteria; AAB89694; AAB89694; AF_1552.
DR   KEGG; afu:AF_1552; -.
DR   eggNOG; arCOG00271; Archaea.
DR   HOGENOM; CLU_033863_9_1_2; -.
DR   OMA; GVQAFYF; -.
DR   PhylomeDB; O28720; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004779; CO/AA/NH_transpt.
DR   InterPro; IPR000620; EamA_dom.
DR   Pfam; PF00892; EamA; 2.
DR   TIGRFAMs; TIGR00950; 2A78; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..270
FT                   /note="Uncharacterized transporter AF_1552"
FT                   /id="PRO_0000108205"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          19..133
FT                   /note="EamA 1"
FT   DOMAIN          150..269
FT                   /note="EamA 2"
SQ   SEQUENCE   270 AA;  29580 MW;  F91071F0019ED544 CRC64;
     MVWFRCMRYG EAAIVLSAVL MGTVSVFVRN VGGDTLSVTF LRLFFGFLAV LPFCLRDVGR
     PDRTLLGLAV FNFLTVASYI AAIQSTEVAM AALLLYMAPV YVIPLSVLMG ERVEVKTLLA
     LPLGLIGLYL MLTPYAELTF GIIFGIVSGL SYAIVFVLSK EARKKHSPWR ITFYNLGLGS
     AALLPYFLMF GRVGSWLWAI GLGVVPTAVP FVLFSYGMKY VKVQRAPILA LIEPLCAGLV
     GYFYFGETLT LTQLIGGAMI LAGVLIAWRE