Y1552_DROME
ID Y1552_DROME Reviewed; 184 AA.
AC Q9VZ40; Q8IR96; Q95U12;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Uncharacterized protein CG1552;
DE Flags: Precursor;
GN ORFNames=CG1552;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1] {ECO:0000312|EMBL:AAF47988.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000269|PubMed:10731132};
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2] {ECO:0000305, ECO:0000312|EMBL:AAF47988.1}
RP GENOME REANNOTATION, AND ALTERNATIVE SPLICING.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [3] {ECO:0000305, ECO:0000312|EMBL:AAL13609.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A), AND RNA EDITING OF
RP POSITION 121.
RC STRAIN=Berkeley; TISSUE=Head {ECO:0000269|PubMed:12537569};
RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA Celniker S.E.;
RT "A Drosophila full-length cDNA resource.";
RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
RN [4] {ECO:0000305}
RP RNA EDITING OF POSITION 121.
RX PubMed=17018572; DOI=10.1261/rna.254306;
RA Stapleton M., Carlson J.W., Celniker S.E.;
RT "RNA editing in Drosophila melanogaster: new targets and functional
RT consequences.";
RL RNA 12:1922-1932(2006).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=A {ECO:0000269|PubMed:10731132};
CC IsoId=Q9VZ40-1; Sequence=Displayed;
CC Name=B {ECO:0000269|PubMed:10731132};
CC IsoId=Q9VZ40-2; Sequence=VSP_052717;
CC -!- RNA EDITING: Modified_positions=121 {ECO:0000269|PubMed:12537569,
CC ECO:0000269|PubMed:17018572}; Note=Partially edited. Target of Adar.
CC {ECO:0000269|PubMed:17018572};
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DR EMBL; AE014298; AAF47988.1; -; Genomic_DNA.
DR EMBL; AE014298; AAN09279.1; -; Genomic_DNA.
DR EMBL; AY058380; AAL13609.1; -; mRNA.
DR RefSeq; NP_001285104.1; NM_001298175.1. [Q9VZ40-1]
DR RefSeq; NP_572676.2; NM_132448.4. [Q9VZ40-1]
DR RefSeq; NP_727479.1; NM_167263.3. [Q9VZ40-2]
DR AlphaFoldDB; Q9VZ40; -.
DR BioGRID; 58450; 1.
DR PaxDb; Q9VZ40; -.
DR DNASU; 32035; -.
DR EnsemblMetazoa; FBtr0073396; FBpp0073252; FBgn0030258. [Q9VZ40-1]
DR EnsemblMetazoa; FBtr0073397; FBpp0073253; FBgn0030258. [Q9VZ40-2]
DR EnsemblMetazoa; FBtr0346272; FBpp0312029; FBgn0030258. [Q9VZ40-1]
DR GeneID; 32035; -.
DR KEGG; dme:Dmel_CG1552; -.
DR UCSC; CG1552-RA; d. melanogaster. [Q9VZ40-1]
DR FlyBase; FBgn0030258; CG1552.
DR VEuPathDB; VectorBase:FBgn0030258; -.
DR eggNOG; ENOG502R0ZG; Eukaryota.
DR InParanoid; Q9VZ40; -.
DR OMA; QIMPRSR; -.
DR PhylomeDB; Q9VZ40; -.
DR BioGRID-ORCS; 32035; 0 hits in 1 CRISPR screen.
DR ChiTaRS; CG1552; fly.
DR GenomeRNAi; 32035; -.
DR PRO; PR:Q9VZ40; -.
DR Proteomes; UP000000803; Chromosome X.
DR Bgee; FBgn0030258; Expressed in brain and 6 other tissues.
DR ExpressionAtlas; Q9VZ40; baseline and differential.
DR Genevisible; Q9VZ40; DM.
DR GO; GO:0005615; C:extracellular space; ISM:FlyBase.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome; RNA editing; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..184
FT /note="Uncharacterized protein CG1552"
FT /id="PRO_0000326432"
FT VAR_SEQ 88..101
FT /note="RSIFVVEKMSRPND -> S (in isoform B)"
FT /evidence="ECO:0000303|PubMed:10731132"
FT /id="VSP_052717"
FT VARIANT 121
FT /note="K -> R (in RNA edited version)"
FT /evidence="ECO:0000269|PubMed:17018572"
SQ SEQUENCE 184 AA; 21452 MW; C8CD61EC2A32035B CRC64;
MYQLEKIWVL LCLALVGVLG FGQFHMKHYQ LQRNYNTQED SGENDNSVLR TFRRCMWEQS
KFLPRRLVLL SLCSNLFCEN NHIMPRSRSI FVVEKMSRPN DCLDILPEQC EQGDEEELMY
KPFPDCCPVY CNLKRRMQRL RTMHFRHRLL RNKQDGSAGS AGGGSAGGDG PNNSLLSEFV
YNNY
