ID   Y1557_STRPN             Reviewed;         282 AA.
AC   Q97PP6;
DT   28-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=DegV domain-containing protein SP_1557;
GN   OrderedLocusNames=SP_1557;
OS   Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=170187;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-334 / TIGR4;
RX   PubMed=11463916; DOI=10.1126/science.1061217;
RA   Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D.,
RA   Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J.,
RA   Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D.,
RA   Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D.,
RA   Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L.,
RA   McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K.,
RA   Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A.,
RA   Morrison D.A., Hollingshead S.K., Fraser C.M.;
RT   "Complete genome sequence of a virulent isolate of Streptococcus
RT   pneumoniae.";
RL   Science 293:498-506(2001).
CC   -!- FUNCTION: May bind long-chain fatty acids, such as palmitate, and may
CC       play a role in lipid transport or fatty acid metabolism. {ECO:0000250}.
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DR   EMBL; AE005672; AAK75644.1; -; Genomic_DNA.
DR   PIR; C95181; C95181.
DR   RefSeq; WP_000762061.1; NZ_AKVY01000001.1.
DR   AlphaFoldDB; Q97PP6; -.
DR   SMR; Q97PP6; -.
DR   STRING; 170187.SP_1557; -.
DR   EnsemblBacteria; AAK75644; AAK75644; SP_1557.
DR   KEGG; spn:SP_1557; -.
DR   eggNOG; COG1307; Bacteria.
DR   OMA; MALGFCA; -.
DR   PhylomeDB; Q97PP6; -.
DR   BioCyc; SPNE170187:G1FZB-1576-MON; -.
DR   Proteomes; UP000000585; Chromosome.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1180.10; -; 1.
DR   InterPro; IPR003797; DegV.
DR   InterPro; IPR043168; DegV_C.
DR   Pfam; PF02645; DegV; 1.
DR   TIGRFAMs; TIGR00762; DegV; 1.
DR   PROSITE; PS51482; DEGV; 1.
PE   3: Inferred from homology;
KW   Lipid-binding.
FT   CHAIN           1..282
FT                   /note="DegV domain-containing protein SP_1557"
FT                   /id="PRO_0000209796"
FT   DOMAIN          3..280
FT                   /note="DegV"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00815"
FT   BINDING         61
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT   BINDING         94
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
SQ   SEQUENCE   282 AA;  30929 MW;  CC4F3C4F2EB81EAC CRC64;
     MKLAVFTDSS AYLSAEILQR EDLFVLDIPV NIDGEEYVEG INLSAEEFYQ KMAQASELPK
     TSQPSIAKLD EILTSLKEQG YTHALGLFLS SGISGFYQNI QYMVDDYEGL TIAFPDTLIT
     SAPLGIMVES VFNWRDQGDD FASIQDKLAI QISRTSAFIM VDDLDHLVKG GRLSNGAAIL
     GNLLSIKPIL YFNDQGVIEV YEKVRTEKKA TKRLIEIIKE TTASGQYRVI VIHGNAPEKA
     EELRQHLLDF GLGSDVSLAT FGSVIGTHLG AGSIALGYIP VI