Y1557_THEMA
ID Y1557_THEMA Reviewed; 222 AA.
AC Q9X1P3;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=UPF0758 protein TM_1557;
GN OrderedLocusNames=TM_1557;
OS Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS / MSB8).
OC Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX NCBI_TaxID=243274;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8;
RX PubMed=10360571; DOI=10.1038/20601;
RA Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A.,
RA Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F.,
RA Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L.,
RA Smith H.O., Venter J.C., Fraser C.M.;
RT "Evidence for lateral gene transfer between Archaea and Bacteria from
RT genome sequence of Thermotoga maritima.";
RL Nature 399:323-329(1999).
CC -!- SIMILARITY: Belongs to the UPF0758 family. {ECO:0000305}.
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DR EMBL; AE000512; AAD36623.1; -; Genomic_DNA.
DR PIR; H72239; H72239.
DR RefSeq; NP_229357.1; NC_000853.1.
DR RefSeq; WP_010865362.1; NZ_CP011107.1.
DR AlphaFoldDB; Q9X1P3; -.
DR SMR; Q9X1P3; -.
DR STRING; 243274.THEMA_06495; -.
DR EnsemblBacteria; AAD36623; AAD36623; TM_1557.
DR KEGG; tma:TM1557; -.
DR KEGG; tmw:THMA_1592; -.
DR PATRIC; fig|243274.19.peg.1562; -.
DR eggNOG; COG2003; Bacteria.
DR InParanoid; Q9X1P3; -.
DR OMA; HEEFWII; -.
DR OrthoDB; 1833204at2; -.
DR Proteomes; UP000008183; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd08071; MPN_DUF2466; 1.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR025657; RadC_JAB.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR001405; UPF0758.
DR InterPro; IPR020891; UPF0758_CS.
DR PANTHER; PTHR30471; PTHR30471; 1.
DR Pfam; PF04002; RadC; 1.
DR SUPFAM; SSF47781; SSF47781; 1.
DR TIGRFAMs; TIGR00608; radc; 1.
DR PROSITE; PS50249; MPN; 1.
DR PROSITE; PS01302; UPF0758; 1.
PE 3: Inferred from homology;
KW Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome;
KW Zinc.
FT CHAIN 1..222
FT /note="UPF0758 protein TM_1557"
FT /id="PRO_0000190747"
FT DOMAIN 101..222
FT /note="MPN"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT MOTIF 171..184
FT /note="JAMM motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 171
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 173
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 184
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
SQ SEQUENCE 222 AA; 24776 MW; D0276495753ED7F1 CRC64;
MKRDGGRLLP RERMIKAGPE SLSVEELVAI VLRTGKKGKH VLELSKDLLE RFDGSLIKLS
NASLEEIASV EGVGMVKAIT LKAALELGKR LHRELERIPE KLDSSVKVYK YCQEMVYLER
EIVKVICLDT KLNVIGENTL TVGTSDRSLI HPRDVFRTAI RANASGVIVV HNHPSGDPTP
SKEDRLITER LKQAGEILGV SLVDHVIVSR RGYFSFREEG EL
