Y1559_ARATH
ID Y1559_ARATH Reviewed; 653 AA.
AC Q84R21; F4I3H6; Q9LG18;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=DUF21 domain-containing protein At1g55930, chloroplastic;
DE AltName: Full=CBS domain-containing protein CBSDUFCH2;
DE Flags: Precursor;
GN Name=CBSDUFCH2; OrderedLocusNames=At1g55930; ORFNames=F14J16.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19400948; DOI=10.1186/1471-2164-10-200;
RA Kushwaha H.R., Singh A.K., Sopory S.K., Singla-Pareek S.L., Pareek A.;
RT "Genome wide expression analysis of CBS domain containing proteins in
RT Arabidopsis thaliana (L.) Heynh and Oryza sativa L. reveals their
RT developmental and stress regulation.";
RL BMC Genomics 10:200-200(2009).
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000305};
CC Multi-pass membrane protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79321.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC002304; AAF79321.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33322.1; -; Genomic_DNA.
DR EMBL; BT006163; AAP04147.1; -; mRNA.
DR EMBL; AK229617; BAF01462.1; -; mRNA.
DR PIR; E96600; E96600.
DR RefSeq; NP_175989.2; NM_104471.6.
DR AlphaFoldDB; Q84R21; -.
DR SMR; Q84R21; -.
DR STRING; 3702.AT1G55930.1; -.
DR iPTMnet; Q84R21; -.
DR PaxDb; Q84R21; -.
DR PRIDE; Q84R21; -.
DR ProteomicsDB; 242391; -.
DR EnsemblPlants; AT1G55930.1; AT1G55930.1; AT1G55930.
DR GeneID; 842044; -.
DR Gramene; AT1G55930.1; AT1G55930.1; AT1G55930.
DR KEGG; ath:AT1G55930; -.
DR Araport; AT1G55930; -.
DR TAIR; locus:2012045; AT1G55930.
DR eggNOG; KOG2118; Eukaryota.
DR HOGENOM; CLU_015237_4_4_1; -.
DR InParanoid; Q84R21; -.
DR OrthoDB; 1369392at2759; -.
DR PRO; PR:Q84R21; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q84R21; baseline and differential.
DR Genevisible; Q84R21; AT.
DR GO; GO:0009941; C:chloroplast envelope; HDA:TAIR.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; -; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF03471; CorC_HlyC; 1.
DR Pfam; PF01595; DUF21; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; SSF54631; 1.
DR SUPFAM; SSF56176; SSF56176; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 2: Evidence at transcript level;
KW CBS domain; Chloroplast; Membrane; Plastid; Reference proteome; Repeat;
KW Transit peptide; Transmembrane; Transmembrane helix; Transport.
FT TRANSIT 1..72
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 73..653
FT /note="DUF21 domain-containing protein At1g55930,
FT chloroplastic"
FT /id="PRO_0000411686"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 280..300
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 149..335
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01193"
FT DOMAIN 354..415
FT /note="CBS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 421..479
FT /note="CBS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT CONFLICT 382
FT /note="S -> P (in Ref. 3; AAP04147 and 4; BAF01462)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 653 AA; 72929 MW; 8986C9B06AE0BE90 CRC64;
MELDLSVLGR SFIVTRRNSS ITRPCIQSSN FSVRVLQRNK HRPLCFSTNP SNSSFIRFQK
GCDFSHRCQF VVLSATGDHV GISQKHSDST EKVDSIRILL KRGIVLGAVV CGVLFYGCGK
VLASTSVVDV AFSKSILLLK NAWPKTSQVL KVLREQGLIL AVLLGLSAFF SMAETSITTL
WPWKVRELAE KEPENGVFRM LRSDVTRFLT TILIGTTVVN IAATALVTKA ATAIFGEAGV
SAATGVMTVA ILLLTEITPK SVAVHNAQEV ARIVVRPVAW LSLILYPVGR VVTYLSMGIL
KILGLKGRSE PYVTEDELKL MLRGAELSGA IEEEEQDMIE NVLEIKDTHV REVMTPLVDV
VAIDGSGSLV DFHNFWVTHQ YSRVPVFEQR IDNIVGIAYA MDLLDYVPKG KLLESTTVVD
MAHKPAFFVP DSMSVWNLLR EFRIRKVHMA VVLNEYGGTI GIVTLEDVVE EIVGEIFDEN
DSKEEIQKKT GYIVMRAEGI YDVDANTSID QLSEELNIKM AEGHQYETVS GFVCEAFGYI
PKTGESVTVV LEKENWEEND EQDEGKHERQ DQKEKHQIYR LEILAGNARK VSAVRFERVS
DMDQVSEARD VKNMVPKFVR KWSSEEDSDG NLQAKNAVFD EHLIAETESM KKE
