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Y1560_METJA
ID   Y1560_METJA             Reviewed;         386 AA.
AC   Q58955;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Uncharacterized MFS-type transporter MJ1560;
GN   OrderedLocusNames=MJ1560;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; L77117; AAB99579.1; -; Genomic_DNA.
DR   PIR; G64494; G64494.
DR   RefSeq; WP_010871084.1; NC_000909.1.
DR   AlphaFoldDB; Q58955; -.
DR   SMR; Q58955; -.
DR   STRING; 243232.MJ_1560; -.
DR   EnsemblBacteria; AAB99579; AAB99579; MJ_1560.
DR   GeneID; 1452468; -.
DR   KEGG; mja:MJ_1560; -.
DR   eggNOG; arCOG00130; Archaea.
DR   HOGENOM; CLU_001265_10_14_2; -.
DR   InParanoid; Q58955; -.
DR   OMA; LYADSFH; -.
DR   OrthoDB; 22281at2157; -.
DR   PhylomeDB; Q58955; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001958; Tet-R_TetA/multi-R_MdtG.
DR   Pfam; PF07690; MFS_1; 1.
DR   PRINTS; PR01035; TCRTETA.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..386
FT                   /note="Uncharacterized MFS-type transporter MJ1560"
FT                   /id="PRO_0000084887"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        272..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        297..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        342..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        365..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   386 AA;  42068 MW;  2B928E8E56D1BFC1 CRC64;
     MGKLEKNVFV IWITTFTTML GVGFIAPIMA IYAQTLGATN LEIGLIFGSF ALARTVAQIP
     VGVLSDIYGK KFFIVCGTFF YGVSTLMYNF VSTVLGFLIV RIFTGIFSAF VTPVAGSYIA
     AIAPKTRLGE YMGIFNSAIT LGFGIGPFIG GILADMYGIK MPFYFCGFLG ILAAIISYMK
     LEDIVFNKNK EKIDVKKIST LFSFEFLKNR NFSSSFIINV SNVMINAGIY AYLALYAINY
     NITISQVGFM IALTNILMAL LQRSFGKLYD KLGNIMIIIG IFIISFGMYL LSTSTTFLTI
     LASLTIIAVG SSISSTATTS LAVKDIPTHR KGEAMGLFTT SINIGMFIGA VSFGFLADIL
     GIANMYKFSA IFSIVVGIIS YLRIER
 
 
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