Y1560_METJA
ID Y1560_METJA Reviewed; 386 AA.
AC Q58955;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Uncharacterized MFS-type transporter MJ1560;
GN OrderedLocusNames=MJ1560;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000305}.
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DR EMBL; L77117; AAB99579.1; -; Genomic_DNA.
DR PIR; G64494; G64494.
DR RefSeq; WP_010871084.1; NC_000909.1.
DR AlphaFoldDB; Q58955; -.
DR SMR; Q58955; -.
DR STRING; 243232.MJ_1560; -.
DR EnsemblBacteria; AAB99579; AAB99579; MJ_1560.
DR GeneID; 1452468; -.
DR KEGG; mja:MJ_1560; -.
DR eggNOG; arCOG00130; Archaea.
DR HOGENOM; CLU_001265_10_14_2; -.
DR InParanoid; Q58955; -.
DR OMA; LYADSFH; -.
DR OrthoDB; 22281at2157; -.
DR PhylomeDB; Q58955; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR001958; Tet-R_TetA/multi-R_MdtG.
DR Pfam; PF07690; MFS_1; 1.
DR PRINTS; PR01035; TCRTETA.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..386
FT /note="Uncharacterized MFS-type transporter MJ1560"
FT /id="PRO_0000084887"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 156..176
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 241..261
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 297..317
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 342..362
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 365..385
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 386 AA; 42068 MW; 2B928E8E56D1BFC1 CRC64;
MGKLEKNVFV IWITTFTTML GVGFIAPIMA IYAQTLGATN LEIGLIFGSF ALARTVAQIP
VGVLSDIYGK KFFIVCGTFF YGVSTLMYNF VSTVLGFLIV RIFTGIFSAF VTPVAGSYIA
AIAPKTRLGE YMGIFNSAIT LGFGIGPFIG GILADMYGIK MPFYFCGFLG ILAAIISYMK
LEDIVFNKNK EKIDVKKIST LFSFEFLKNR NFSSSFIINV SNVMINAGIY AYLALYAINY
NITISQVGFM IALTNILMAL LQRSFGKLYD KLGNIMIIIG IFIISFGMYL LSTSTTFLTI
LASLTIIAVG SSISSTATTS LAVKDIPTHR KGEAMGLFTT SINIGMFIGA VSFGFLADIL
GIANMYKFSA IFSIVVGIIS YLRIER