ID   Y1561_METS3             Reviewed;         345 AA.
AC   A5UNI8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=UPF0219 protein Msm_1561 {ECO:0000255|HAMAP-Rule:MF_01409};
GN   OrderedLocusNames=Msm_1561;
OS   Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX   NCBI_TaxID=420247;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35061 / DSM 861 / OCM 144 / PS;
RX   PubMed=17563350; DOI=10.1073/pnas.0704189104;
RA   Samuel B.S., Hansen E.E., Manchester J.K., Coutinho P.M., Henrissat B.,
RA   Fulton R., Latreille P., Kim K., Wilson R.K., Gordon J.I.;
RT   "Genomic and metabolic adaptations of Methanobrevibacter smithii to the
RT   human gut.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:10643-10648(2007).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. UPF0219 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01409}.
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DR   EMBL; CP000678; ABQ87766.1; -; Genomic_DNA.
DR   RefSeq; WP_004035269.1; NC_009515.1.
DR   AlphaFoldDB; A5UNI8; -.
DR   SMR; A5UNI8; -.
DR   STRING; 420247.Msm_1561; -.
DR   EnsemblBacteria; ABQ87766; ABQ87766; Msm_1561.
DR   GeneID; 5217314; -.
DR   KEGG; msi:Msm_1561; -.
DR   PATRIC; fig|420247.28.peg.1551; -.
DR   eggNOG; arCOG01767; Archaea.
DR   HOGENOM; CLU_039592_7_0_2; -.
DR   OMA; YAKHKGK; -.
DR   BioCyc; MSMI420247:GHWZ-1601-MON; -.
DR   Proteomes; UP000001992; Chromosome.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 1.
DR   HAMAP; MF_01409; UPF0219; 1.
DR   InterPro; IPR013747; ACP_syn_III_C.
DR   InterPro; IPR004656; FabH-rel.
DR   InterPro; IPR013528; HMG_CoA_synth_N.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF08541; ACP_syn_III_C; 1.
DR   Pfam; PF01154; HMG_CoA_synt_N; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR00748; HMG_CoA_syn_Arc; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..345
FT                   /note="UPF0219 protein Msm_1561"
FT                   /id="PRO_1000068443"
SQ   SEQUENCE   345 AA;  36976 MW;  BE491CA14BDB21C6 CRC64;
     MVGIVGYGAY VPSYRIKVEE IAKVWGDDPV ALSRGLVVNE KSVPSADEDT ATIAVTAARY
     ALARAQIDPQ KIGAIYVGSE SHPYAVKPSA TIVAEAINAT PDLTAADLEF ACKAGTAGIQ
     MTMGLVDSDM IEYGLAIGAD TSQGAPGDAL EYTASAGGAA YIIGKDNTLA DIEETYSFTT
     DTPDFYRREG QDYPSHGGRF TGEPAYFKHV LSAAKGLFEK TDSKPEDYDY ACFHQPNGKF
     YLRAGKKLGF TSEQIKQGLL TPNIGNTYSG AVPLALSNIL DVAEPGDKIF VVSYGSGAGS
     DGFTLTVNEE IKEKRDLAPK TQDIIDRKQY VDYAVYAKFK GKIKM