ID   Y1563_STRP8             Reviewed;         142 AA.
AC   Q8P051;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Uncharacterized acetyltransferase spyM18_1563;
DE            EC=2.3.1.-;
GN   OrderedLocusNames=spyM18_1563;
OS   Streptococcus pyogenes serotype M18 (strain MGAS8232).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=186103;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGAS8232;
RX   PubMed=11917108; DOI=10.1073/pnas.062526099;
RA   Smoot J.C., Barbian K.D., Van Gompel J.J., Smoot L.M., Chaussee M.S.,
RA   Sylva G.L., Sturdevant D.E., Ricklefs S.M., Porcella S.F., Parkins L.D.,
RA   Beres S.B., Campbell D.S., Smith T.M., Zhang Q., Kapur V., Daly J.A.,
RA   Veasy L.G., Musser J.M.;
RT   "Genome sequence and comparative microarray analysis of serotype M18 group
RT   A Streptococcus strains associated with acute rheumatic fever outbreaks.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4668-4673(2002).
CC   -!- SIMILARITY: Belongs to the acetyltransferase family. {ECO:0000305}.
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DR   EMBL; AE009949; AAL98128.1; -; Genomic_DNA.
DR   RefSeq; WP_011018013.1; NC_003485.1.
DR   AlphaFoldDB; Q8P051; -.
DR   SMR; Q8P051; -.
DR   KEGG; spm:spyM18_1563; -.
DR   HOGENOM; CLU_056607_9_0_9; -.
DR   OMA; HYLTIHA; -.
DR   GO; GO:0004343; F:glucosamine 6-phosphate N-acetyltransferase activity; IEA:InterPro.
DR   GO; GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; IEA:InterPro.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR039143; GNPNAT1.
DR   PANTHER; PTHR13355; PTHR13355; 1.
DR   Pfam; PF13673; Acetyltransf_10; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Transferase.
FT   CHAIN           1..142
FT                   /note="Uncharacterized acetyltransferase spyM18_1563"
FT                   /id="PRO_0000205423"
FT   DOMAIN          1..120
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00532"
SQ   SEQUENCE   142 AA;  16142 MW;  08DFA68072F25EEA CRC64;
     MTDKFDANDE TRTVYAVVYD NDQPVSTGQF LAETKIEARL TRIVTLADYC GCGYGAKVTE
     ALETYTRREG FYQLTIHSEL TAQTFYENLG YQTYGSKYLE DGEYCQSLVK TILKWEKNMD
     IAMLIAIVGG LLGCYLYLTK NN