ID   Y1565_METJA             Reviewed;         513 AA.
AC   Q58960;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Probable helicase MJ1565 {ECO:0000305};
DE            EC=3.6.4.12 {ECO:0000250|UniProtKB:F2Z5Z6};
GN   OrderedLocusNames=MJ1565 {ECO:0000312|EMBL:AAB99585.1};
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000250|UniProtKB:F2Z5Z6};
CC   -!- SIMILARITY: Belongs to the HerA family. {ECO:0000305}.
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DR   EMBL; L77117; AAB99585.1; -; Genomic_DNA.
DR   PIR; D64495; D64495.
DR   RefSeq; WP_010871089.1; NC_000909.1.
DR   AlphaFoldDB; Q58960; -.
DR   SMR; Q58960; -.
DR   STRING; 243232.MJ_1565; -.
DR   DNASU; 1452473; -.
DR   EnsemblBacteria; AAB99585; AAB99585; MJ_1565.
DR   GeneID; 1452473; -.
DR   KEGG; mja:MJ_1565; -.
DR   eggNOG; arCOG00280; Archaea.
DR   HOGENOM; CLU_023842_2_0_2; -.
DR   InParanoid; Q58960; -.
DR   OMA; CLVSQRP; -.
DR   OrthoDB; 33242at2157; -.
DR   PhylomeDB; Q58960; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR008571; HerA-like.
DR   InterPro; IPR018538; HerA_barrel_dom.
DR   InterPro; IPR033186; HerA_C.
DR   InterPro; IPR002789; HerA_central.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR42957; PTHR42957; 1.
DR   Pfam; PF05872; DUF853; 1.
DR   Pfam; PF01935; DUF87; 1.
DR   Pfam; PF09378; HAS-barrel; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..513
FT                   /note="Probable helicase MJ1565"
FT                   /id="PRO_0000107413"
FT   BINDING         151
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:Q97WG8"
FT   BINDING         160..165
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:Q97WG8"
FT   BINDING         467..468
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:Q97WG8"
SQ   SEQUENCE   513 AA;  58672 MW;  A45C1EAD7D932526 CRC64;
     MDNNEIIGYT IGETRIDELT FLAKEAPKVG DYVKINYDDS ELLGMVESTI QGNMALEDIL
     NIEHLEKIRE FEDNSSYYIL GKIKVLGDIR DLNKDGALKL PRVPPKPGIP IYRADDELLK
     KVFGNGHLKI GHLVTREDVE VKLDANKLCS RHLAILAMTG MGKSNTVAVL LRELNKLKAT
     VLVFDMHGEY KDIYCESEKL RVHIIEPKIN IYRINDDDLC DLAGVDAQAT KQRPYIRKAI
     KEIKEERKEH DFSTVDDYIN AIIGKLEEYK SNDNYKKDES SIQTAIFRLE DMLQFRKNII
     TLHYNPINDI REHYINIIPM EELDENAVDI VVSYIAKAVL DDRKRIIIDK GRDFAKPIFM
     IFEEAHLIAP QHRKTRAKHY LSRIAREGRK FGVGLCLVSQ RPKTLDAETL SQCSNLIISK
     LIEPTDQKHV QMASENLSED LVKQLTSLNI GEAIILGPCI KVPAIVKVDK FDGRYGGEDL
     NLVELWEKDF INTERLKTDD IEENAFGDDD LFS