ID   Y1574_METJA             Reviewed;         684 AA.
AC   Q58969;
DT   03-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Uncharacterized ATP-dependent helicase MJ1574;
DE            EC=3.6.4.-;
GN   OrderedLocusNames=MJ1574;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SIMILARITY: Belongs to the helicase family. {ECO:0000305}.
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DR   EMBL; L77117; AAB99590.1; -; Genomic_DNA.
DR   PIR; E64496; E64496.
DR   RefSeq; WP_010871099.1; NC_000909.1.
DR   AlphaFoldDB; Q58969; -.
DR   SMR; Q58969; -.
DR   STRING; 243232.MJ_1574; -.
DR   EnsemblBacteria; AAB99590; AAB99590; MJ_1574.
DR   GeneID; 1452483; -.
DR   KEGG; mja:MJ_1574; -.
DR   eggNOG; arCOG00555; Archaea.
DR   HOGENOM; CLU_000809_3_2_2; -.
DR   InParanoid; Q58969; -.
DR   PhylomeDB; Q58969; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0043138; F:3'-5' DNA helicase activity; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006289; P:nucleotide-excision repair; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..684
FT                   /note="Uncharacterized ATP-dependent helicase MJ1574"
FT                   /id="PRO_0000102200"
FT   DOMAIN          54..239
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   DOMAIN          264..419
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT   MOTIF           181..184
FT                   /note="DEVH box"
FT   BINDING         67..74
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ   SEQUENCE   684 AA;  81280 MW;  B60E8AFC0C6A49AE CRC64;
     MEDVFKGIEK EIIKIYKIPE RKGRFSNFKF KNKEINELID ALGFKLYLHQ VKALKYLYNK
     KDVVVTTSTA SGKSEIFRLA IFDNFLSNPD DRYLLIYPTR ALINNQYEKF SMENELFYKI
     TNKRVKAEIL TGDVGLEKRR EILKDKPNVL FTTPDMLHYQ ILKNHNNYLW LLKNLKLLVV
     DELHVYRGVF GTNMVYVFKR LLKLLKRLNN NLQILCLSAT LKNPKEFVKL LFNRDFEVVD
     KSYNPSSRKY LAILEPKNLD NKQLLRRLIE NLVDNNIKTL VFFDTRKETE KLMRFLLNSK
     VFYKLSTYKG TLPKYVREEI EEKFKNGEIL ALLTTNALEL GIDIGDLDAV INYGIPPDGI
     FSLIQRFGRA GRRDKEALNI IVLRKDGLDY YYKEHLNELY ERIRKGIIEY MPVNIKNRFV
     TKKHLHYLIS ELKIVDFDEL NDFEKEIVKE LEREGKIKIY KNPITNKTEI RNVKQPIYSS
     IRTASDESYY LILDKPWIKS KLLNKTQSEI LSFINWLKIK GYVIEEVDKD EYYRSLITGM
     PYFSRGKLFI AKDKIGIRKF HFIFADELDM FWDVEALQKK EEEIDILDIY DKKSYKDIDI
     YYGRLRVRKI YEGFIVRGVD VDKYYQELLA LKDNGILDAE IDLFKDFFGL NFISVKFNKK
     IIRDFETDGI WLCYFQIILG MLTK