ID   Y1574_STAES             Reviewed;         328 AA.
AC   Q8CRU8;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=UPF0421 protein SE_1574;
GN   OrderedLocusNames=SE_1574;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0421 family. {ECO:0000305}.
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DR   EMBL; AE015929; AAO05173.1; -; Genomic_DNA.
DR   RefSeq; NP_765129.1; NC_004461.1.
DR   RefSeq; WP_011082745.1; NZ_WBME01000010.1.
DR   AlphaFoldDB; Q8CRU8; -.
DR   SMR; Q8CRU8; -.
DR   STRING; 176280.SE_1574; -.
DR   EnsemblBacteria; AAO05173; AAO05173; SE_1574.
DR   KEGG; sep:SE_1574; -.
DR   PATRIC; fig|176280.10.peg.1538; -.
DR   eggNOG; COG4129; Bacteria.
DR   HOGENOM; CLU_067028_0_0_9; -.
DR   OMA; ANVMEEW; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010343; ArAE_1.
DR   Pfam; PF06081; ArAE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..328
FT                   /note="UPF0421 protein SE_1574"
FT                   /id="PRO_0000283024"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   328 AA;  37381 MW;  D0999D834319DF7D CRC64;
     MNDKWYRHII GARTIKTGLA TFFTSLFCML LNLTPIFAIL TAIVTIEPTA KASLKKGYKR
     LPATVIGALF AVVFTYVFGD QSPLSYALSA TFTILICTKL NLQVGTTVAV LTSVAMIPSI
     HEAYVFNFFS RLLTALIGLV TAGLVNFIIL PPKYYHQLEE QLALSEKKMY RLFYERCNEL
     LLGKFSSEKT SKELSKLNII AQKVETLMSY QRDELHYHKN EDNWKLLNRL TNRAYNNRLF
     ISHLSNIIYL PKHTSIAFDA NEKIALINIS NSINGIIQKG SFARQKKSIA TLKSSVKQMD
     EFDQNQMKST LIYEILLIYK ILDSRYAK