ID   Y1575_AQUAE             Reviewed;         249 AA.
AC   O67517;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Probable transcriptional regulatory protein aq_1575 {ECO:0000255|HAMAP-Rule:MF_00693};
GN   OrderedLocusNames=aq_1575;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (1.72 ANGSTROMS).
RX   PubMed=12060744; DOI=10.1073/pnas.132241399;
RA   Shin D.H., Yokota H., Kim R., Kim S.H.;
RT   "Crystal structure of conserved hypothetical protein Aq1575 from Aquifex
RT   aeolicus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:7980-7985(2002).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00693}.
CC   -!- SIMILARITY: Belongs to the TACO1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00693}.
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DR   EMBL; AE000657; AAC07491.1; -; Genomic_DNA.
DR   PIR; C70436; C70436.
DR   RefSeq; NP_214082.1; NC_000918.1.
DR   RefSeq; WP_010881020.1; NC_000918.1.
DR   PDB; 1LFP; X-ray; 1.72 A; A=1-249.
DR   PDBsum; 1LFP; -.
DR   AlphaFoldDB; O67517; -.
DR   SMR; O67517; -.
DR   STRING; 224324.aq_1575; -.
DR   EnsemblBacteria; AAC07491; AAC07491; aq_1575.
DR   KEGG; aae:aq_1575; -.
DR   PATRIC; fig|224324.8.peg.1216; -.
DR   eggNOG; COG0217; Bacteria.
DR   HOGENOM; CLU_062974_2_2_0; -.
DR   InParanoid; O67517; -.
DR   OMA; ETIMYEG; -.
DR   OrthoDB; 1304328at2; -.
DR   EvolutionaryTrace; O67517; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.200; -; 1.
DR   Gene3D; 3.30.70.980; -; 2.
DR   HAMAP; MF_00693; Transcrip_reg_TACO1; 1.
DR   InterPro; IPR017856; Integrase-like_N.
DR   InterPro; IPR002876; Transcrip_reg_TACO1-like.
DR   InterPro; IPR026564; Transcrip_reg_TACO1-like_dom3.
DR   InterPro; IPR029072; YebC-like.
DR   PANTHER; PTHR12532; PTHR12532; 1.
DR   Pfam; PF01709; Transcrip_reg; 1.
DR   SUPFAM; SSF75625; SSF75625; 1.
DR   TIGRFAMs; TIGR01033; TIGR01033; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..249
FT                   /note="Probable transcriptional regulatory protein aq_1575"
FT                   /id="PRO_0000175750"
FT   STRAND          10..15
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   TURN            17..19
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           21..39
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           43..45
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           47..58
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           63..74
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   STRAND          77..79
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   STRAND          83..91
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   TURN            92..94
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   STRAND          95..104
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           106..119
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           131..133
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   STRAND          134..143
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           144..146
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           149..159
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   STRAND          162..165
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   STRAND          168..175
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           177..179
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           180..188
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   TURN            189..191
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   STRAND          195..205
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   HELIX           212..226
FT                   /evidence="ECO:0007829|PDB:1LFP"
FT   STRAND          231..236
FT                   /evidence="ECO:0007829|PDB:1LFP"
SQ   SEQUENCE   249 AA;  27863 MW;  B138F960624CE6AC CRC64;
     MAGHSHWAQI KHKKAKVDAQ RGKLFSKLIR EIIVATRLGG PNPEFNPRLR TAIEQAKKAN
     MPWENIERAI KKGAGELEGE QFEEVIYEGY APGGVAVMVL ATTDNRNRTT SEVRHVFTKH
     GGNLGASGCV SYLFERKGYI EVPAKEVSEE ELLEKAIEVG AEDVQPGEEV HIIYTVPEEL
     YEVKENLEKL GVPIEKAQIT WKPISTVQIN DEETAQKVIK LLNALEELDD VQQVIANFEI
     PEEILQKVG