Y1576_ARATH
ID Y1576_ARATH Reviewed; 329 AA.
AC Q680K8; Q9LFZ6;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=BTB/POZ domain-containing protein At1g55760;
GN OrderedLocusNames=At1g55760; ORFNames=F20N2.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis cDNA clones.";
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP DOMAIN BTB.
RX PubMed=15749712; DOI=10.1074/jbc.m413247200;
RA Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L.,
RA Vierstra R.D.;
RT "Cullins 3a and 3b assemble with members of the broad
RT complex/tramtrack/bric-a-brac (BTB) protein family to form essential
RT ubiquitin-protein ligases (E3s) in Arabidopsis.";
RL J. Biol. Chem. 280:18810-18821(2005).
CC -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC ubiquitination and subsequent proteasomal degradation of target
CC proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- DOMAIN: The BTB/POZ domain mediates the interaction with some component
CC of ubiquitin ligase complexes. {ECO:0000269|PubMed:15749712}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79503.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At1g55750 and At1g55760.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC002328; AAF79503.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33294.1; -; Genomic_DNA.
DR EMBL; AK175625; BAD43388.1; -; mRNA.
DR EMBL; AK175859; BAD43622.1; -; mRNA.
DR EMBL; BT022097; AAY34158.1; -; mRNA.
DR RefSeq; NP_175972.1; NM_104452.4.
DR AlphaFoldDB; Q680K8; -.
DR SMR; Q680K8; -.
DR BioGRID; 27250; 1.
DR IntAct; Q680K8; 1.
DR STRING; 3702.AT1G55760.1; -.
DR PaxDb; Q680K8; -.
DR PRIDE; Q680K8; -.
DR ProteomicsDB; 243053; -.
DR EnsemblPlants; AT1G55760.1; AT1G55760.1; AT1G55760.
DR GeneID; 842025; -.
DR Gramene; AT1G55760.1; AT1G55760.1; AT1G55760.
DR KEGG; ath:AT1G55760; -.
DR Araport; AT1G55760; -.
DR TAIR; locus:2020522; AT1G55760.
DR eggNOG; KOG1987; Eukaryota.
DR HOGENOM; CLU_061287_0_0_1; -.
DR OMA; HDGFVWA; -.
DR OrthoDB; 864323at2759; -.
DR PhylomeDB; Q680K8; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q680K8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q680K8; baseline and differential.
DR Genevisible; Q680K8; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0009651; P:response to salt stress; IMP:TAIR.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR044714; AtSIBP1-like.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR46672; PTHR46672; 1.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
DR PROSITE; PS50097; BTB; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..329
FT /note="BTB/POZ domain-containing protein At1g55760"
FT /id="PRO_0000406091"
FT DOMAIN 164..231
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
SQ SEQUENCE 329 AA; 37669 MW; E1567B7F6C434965 CRC64;
MTDSAYRVDT ISRLAQWRIH NLSSSTYRKS DPFKMGLWNW HLSVEKSKML LNVKLYPEVS
NLTRENPPVA SFALRVVSST GERKALSHPE VIDKRIKTNE DFIWTIEVPL TGKIIIDVEF
LDLKVLSQDS GELYSIWANG STENQSQVTA VTSLGRMLTE SIYTDITINA SDGSIGAHRA
VLAARSPVFR SMFLHDLKEK ELSEINVLDM PLDACQAFLS YIYGNIQNED FLIHRLALLQ
AAEKYDIADL KEACHLSLLD DIDTKNVLER LQNAYLYQLP ELKASCMRYL VKFGKIFEIR
DEFNIFMQCA DRDLISEIFH EVLSTWKGF
