ID   Y1581_MYCBO             Reviewed;         202 AA.
AC   P67437; A0A1R3XZK8; Q10774; Q79FM7; X2BI74;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator Mb1581;
GN   OrderedLocusNames=BQ2027_MB1581;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
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DR   EMBL; LT708304; SIU00184.1; -; Genomic_DNA.
DR   RefSeq; NP_855233.1; NC_002945.3.
DR   RefSeq; WP_003407773.1; NC_002945.4.
DR   AlphaFoldDB; P67437; -.
DR   SMR; P67437; -.
DR   EnsemblBacteria; SIU00184; SIU00184; BQ2027_MB1581.
DR   GeneID; 45425539; -.
DR   PATRIC; fig|233413.5.peg.1728; -.
DR   OMA; HQFLDQR; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProt.
DR   InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   InterPro; IPR011075; TetR_C.
DR   Pfam; PF16859; TetR_C_11; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF48498; SSF48498; 1.
DR   PROSITE; PS01081; HTH_TETR_1; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Repeat; Transcription; Transcription regulation.
FT   CHAIN           1..202
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   Mb1581"
FT                   /id="PRO_0000070663"
FT   DOMAIN          19..79
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   202 AA;  22330 MW;  6754AD8609195C42 CRC64;
     MVGAVTQIAD RPTDPSPWSP RETELLAVTL RLLQEHGYDR LTVDAVAASA RASKATVYRR
     WPSKAELVLA AFIEGIRQVA VPPNTGNLRD DLLRLGELIC REVGQHASTI RAVLVEVSRN
     PALNDVLQHQ FVDHRKALIQ YILQQAVDRG EISSAAISDE LWDLLPGYLI FRSIIPNRPP
     TQDTVQALVD DVILPSLTRS TG