ID   Y1592_MYCTO             Reviewed;         446 AA.
AC   P9WK88; L0T740; O06598; Q8VK00;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=Probable inactive lipase MT1628;
GN   OrderedLocusNames=MT1628;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Although related to the lipase family, lacks the conserved His
CC       active site at position 344 which is replaced by a Gln residue,
CC       suggesting it is inactive. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK45896.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000516; AAK45896.1; ALT_INIT; Genomic_DNA.
DR   PIR; B70543; B70543.
DR   RefSeq; WP_003407926.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WK88; -.
DR   SMR; P9WK88; -.
DR   ESTHER; myctu-MT1628; Fungal-Bact_LIP.
DR   EnsemblBacteria; AAK45896; AAK45896; MT1628.
DR   KEGG; mtc:MT1628; -.
DR   PATRIC; fig|83331.31.peg.1750; -.
DR   HOGENOM; CLU_029538_5_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR005152; Lipase_secreted.
DR   PANTHER; PTHR34853; PTHR34853; 1.
DR   Pfam; PF03583; LIP; 1.
DR   PIRSF; PIRSF029171; Esterase_LipA; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..446
FT                   /note="Probable inactive lipase MT1628"
FT                   /id="PRO_0000427696"
SQ   SEQUENCE   446 AA;  48029 MW;  C93BAA6B0DCC6A18 CRC64;
     MVEPGNLAGA TGAEWIGRPP HEELQRKVRP LLPSDDPFYF PPAGYQHAVP GTVLRSRDVE
     LAFMGLIPQP VTATQLLYRT TNMYGNPEAT VTTVIVPAEL APGQTCPLLS YQCAIDAMSS
     RCFPSYALRR RAKALGSLTQ MELLMISAAL AEGWAVSVPD HEGPKGLWGS PYEPGYRVLD
     GIRAALNSER VGLSPATPIG LWGYSGGGLA SAWAAEACGE YAPDLDIVGA VLGSPVGDLG
     HTFRRLNGTL LAGLPALVVA ALQHSYPGLA RVIKEHANDE GRQLLEQLTE MTTVDAVIRM
     AGRDMGDFLD EPLEDILSTP EVSHVFGDTK LGSAVPTPPV LIVQAVHDYL IDVSDIDALA
     DSYTAGGANV TYHRDLFSEH VSLHPLSAPM TLRWLTDRFA GKPLTDHRVR TTWPTIFNPM
     TYAGMARLAV IAAKVITGRK LSRRPL