ID   Y1608_STRP1             Reviewed;         177 AA.
AC   Q99YP1; Q48XI6;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=UPF0374 protein SPy_1608/M5005_Spy1321 {ECO:0000255|HAMAP-Rule:MF_01568};
GN   OrderedLocusNames=SPy_1608, M5005_Spy1321;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- SIMILARITY: Belongs to the UPF0374 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01568}.
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DR   EMBL; AE004092; AAK34385.1; -; Genomic_DNA.
DR   EMBL; CP000017; AAZ51939.1; -; Genomic_DNA.
DR   RefSeq; NP_269664.1; NC_002737.2.
DR   AlphaFoldDB; Q99YP1; -.
DR   SMR; Q99YP1; -.
DR   STRING; 1314.HKU360_01360; -.
DR   PaxDb; Q99YP1; -.
DR   DNASU; 901859; -.
DR   EnsemblBacteria; AAK34385; AAK34385; SPy_1608.
DR   KEGG; spy:SPy_1608; -.
DR   KEGG; spz:M5005_Spy1321; -.
DR   PATRIC; fig|160490.10.peg.1402; -.
DR   HOGENOM; CLU_109787_1_0_9; -.
DR   OMA; QSYKHNG; -.
DR   Proteomes; UP000000750; Chromosome.
DR   Gene3D; 2.40.380.10; -; 1.
DR   HAMAP; MF_01568; UPF0374; 1.
DR   InterPro; IPR007295; DUF402.
DR   InterPro; IPR035930; FomD-like_sf.
DR   InterPro; IPR016882; UPF0374.
DR   Pfam; PF04167; DUF402; 1.
DR   PIRSF; PIRSF028345; UCP028345; 1.
DR   SUPFAM; SSF159234; SSF159234; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..177
FT                   /note="UPF0374 protein SPy_1608/M5005_Spy1321"
FT                   /id="PRO_0000248121"
SQ   SEQUENCE   177 AA;  21178 MW;  EA656E27864DF4D2 CRC64;
     MKLPKEGDFI TIQSYKHDGS LHRTWRDTMV LKTTENALIG VNDHTLVTES DGRRWVTREP
     AIVYFHKKYW FNIIAMIRDN GVSYYCNLAS PYMMDTEALK YIDYDLDVKV FADGEKRLLD
     VDEYEIHKKE MQYSADMDFI LKENVKILVD WINHEKGPFS KAYITIWYKR YLELKNR