ID   Y1610_AQUAE             Reviewed;         231 AA.
AC   O67541;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=UPF0758 protein aq_1610;
GN   OrderedLocusNames=aq_1610;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- SIMILARITY: Belongs to the UPF0758 family. {ECO:0000305}.
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DR   EMBL; AE000657; AAC07500.1; -; Genomic_DNA.
DR   PIR; C70439; C70439.
DR   RefSeq; NP_214106.1; NC_000918.1.
DR   RefSeq; WP_010881044.1; NC_000918.1.
DR   AlphaFoldDB; O67541; -.
DR   SMR; O67541; -.
DR   STRING; 224324.aq_1610; -.
DR   EnsemblBacteria; AAC07500; AAC07500; aq_1610.
DR   KEGG; aae:aq_1610; -.
DR   PATRIC; fig|224324.8.peg.1244; -.
DR   eggNOG; COG2003; Bacteria.
DR   HOGENOM; CLU_073529_0_2_0; -.
DR   InParanoid; O67541; -.
DR   OMA; AMPDYEL; -.
DR   OrthoDB; 1833204at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd08071; MPN_DUF2466; 1.
DR   InterPro; IPR037518; MPN.
DR   InterPro; IPR025657; RadC_JAB.
DR   InterPro; IPR001405; UPF0758.
DR   InterPro; IPR020891; UPF0758_CS.
DR   PANTHER; PTHR30471; PTHR30471; 1.
DR   Pfam; PF04002; RadC; 1.
DR   TIGRFAMs; TIGR00608; radc; 1.
DR   PROSITE; PS50249; MPN; 1.
DR   PROSITE; PS01302; UPF0758; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome;
KW   Zinc.
FT   CHAIN           1..231
FT                   /note="UPF0758 protein aq_1610"
FT                   /id="PRO_0000190677"
FT   DOMAIN          110..231
FT                   /note="MPN"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT   MOTIF           180..193
FT                   /note="JAMM motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT   BINDING         180
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT   BINDING         182
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT   BINDING         193
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
SQ   SEQUENCE   231 AA;  26215 MW;  F76974A14E7DC0CE CRC64;
     MGQARDRVNY SFKRLKEIPE ELRPREKLLK LGPENLSDEE LLAVILGSGS KGADVLSLSK
     ELIKMGWEEL EKKSVEELLK VRGLGLVKAL QVKALVELSK RFKGGKSRIS IRNPQEAFEF
     LKDKFDERRE SLIALYLDLS NRLLDWEVVA IGNVNTVFSK PKDILFKAVK LSANGIIIAH
     NHPQGEPSPS NEDLNFTERL KKACELLGFE LLDHLILSEG RYFSFREEGV L