ID   Y1617_MYCBO             Reviewed;         193 AA.
AC   P0A5F4; A0A1R3XYQ7; O06599; O52590; X2BID8;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Uncharacterized protein Mb1617;
GN   OrderedLocusNames=BQ2027_MB1617;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BCG / Pasteur;
RA   Yu S., Jacobs W.R. Jr.;
RT   "Cloning, sequencing, and identification of Mycobacterium bovis BCG biotin
RT   biosynthetic genes by complementing two Mycobacterium smegmatis biotin
RT   mutants.";
RL   Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.leprae ML1222. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=SIU00221.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AF041819; AAB96963.1; -; Genomic_DNA.
DR   EMBL; LT708304; SIU00221.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_855270.1; NC_002945.3.
DR   AlphaFoldDB; P0A5F4; -.
DR   EnsemblBacteria; SIU00221; SIU00221; BQ2027_MB1617.
DR   PATRIC; fig|233413.5.peg.1766; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR021213; DUF2567.
DR   Pfam; PF10821; DUF2567; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..193
FT                   /note="Uncharacterized protein Mb1617"
FT                   /id="PRO_0000103892"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   193 AA;  20299 MW;  2B4494E423DC636D CRC64;
     MLGLSATGVL VGGLWAWIAP PIHAVVAITR AGERVHEYLG SESQNFFIAP FMLLGLLSVL
     AVVASALMWQ WREHRGPQMV AGLSIGLTTA AAIAAGVGAL VVRLRYGALD FDTVPLSRGD
     HALTYVTQAP PVFFARRPLQ IALTLMWPAG IASLVYALLA AGTARDDLGG YPAVDPSSNA
     RTEALETPQA PVS