ID   Y1620_METJA             Reviewed;         505 AA.
AC   Q59015;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Uncharacterized protein MJ1620;
GN   OrderedLocusNames=MJ1620;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU01266};
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DR   EMBL; L77117; AAB99641.1; -; Genomic_DNA.
DR   PIR; C64502; C64502.
DR   RefSeq; WP_010871145.1; NC_000909.1.
DR   AlphaFoldDB; Q59015; -.
DR   SMR; Q59015; -.
DR   STRING; 243232.MJ_1620; -.
DR   EnsemblBacteria; AAB99641; AAB99641; MJ_1620.
DR   GeneID; 1452529; -.
DR   KEGG; mja:MJ_1620; -.
DR   eggNOG; arCOG01356; Archaea.
DR   HOGENOM; CLU_508670_0_0_2; -.
DR   InParanoid; Q59015; -.
DR   OMA; GLRPYVY; -.
DR   OrthoDB; 9274at2157; -.
DR   PhylomeDB; Q59015; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.30.20; -; 1.
DR   InterPro; IPR006158; Cobalamin-bd.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   InterPro; IPR002792; TRAM_dom.
DR   Pfam; PF02310; B12-binding; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   Pfam; PF01938; TRAM; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SMART; SM00729; Elp3; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
DR   PROSITE; PS50926; TRAM; 1.
PE   4: Predicted;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..505
FT                   /note="Uncharacterized protein MJ1620"
FT                   /id="PRO_0000107441"
FT   DOMAIN          193..440
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   DOMAIN          435..499
FT                   /note="TRAM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00208"
FT   BINDING         208
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         216
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         219
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
SQ   SEQUENCE   505 AA;  57466 MW;  949F2318DF8D7404 CRC64;
     MKALIIDCLA SGDGKRILAR DVIGAGPRTV KGILQSEGIE AKITPVEDLD IKDIKKYNLI
     FISAMTSDFK CVKKLVERIR LKTDSKIIVG GPIANDINIL EKIEADISIV GEGEITIREL
     IKKDFDAEDV KGTTYWDYNE DELKINPLRE ILTDLKLITP STEIKDYKNY FSARVYVEVV
     RGCSNFKRPL LLCTNKKCNL CENGTLKCPL NINPGCGFCS VPSVFGYARS RDEEDILKEV
     EALLKEGVNR IVLSAPDFLD YKRGEKLINP YFPEPNYEAI ESLLSKCKDL ADKYNANVLI
     ENIKANLFNE KVAEIFSKYL KTPIYIGCES GDKNHCKLLG RPTTPDDVLK AVKIAKKYNL
     KAQVYFIYGL PGENEETAKN TVNFMHKIKN YIDKITVYKF RPLPMSAFQN FKPNITKYSL
     LIRETANKIN LEIKKKYIGR VLEVIISERH FRNKRDAIGY LPDSGLMVVV KDGAKFIGKT
     KKVKIIKAYE KYLEGRILKT WLCKY