Y1624_MYCLE
ID Y1624_MYCLE Reviewed; 596 AA.
AC O33011;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 109.
DE RecName: Full=Uncharacterized protein ML1624;
GN OrderedLocusNames=ML1624; ORFNames=MLCB250.18c;
OS Mycobacterium leprae (strain TN).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=272631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TN;
RX PubMed=11234002; DOI=10.1038/35059006;
RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA Barrell B.G.;
RT "Massive gene decay in the leprosy bacillus.";
RL Nature 409:1007-1011(2001).
CC -!- SIMILARITY: To M.tuberculosis Rv2917. {ECO:0000305}.
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DR EMBL; Z97369; CAB10612.1; -; Genomic_DNA.
DR EMBL; AL583922; CAC30575.1; -; Genomic_DNA.
DR PIR; B87112; B87112.
DR RefSeq; NP_302119.1; NC_002677.1.
DR RefSeq; WP_010908440.1; NC_002677.1.
DR AlphaFoldDB; O33011; -.
DR STRING; 272631.ML1624; -.
DR EnsemblBacteria; CAC30575; CAC30575; CAC30575.
DR KEGG; mle:ML1624; -.
DR PATRIC; fig|272631.5.peg.3059; -.
DR Leproma; ML1624; -.
DR eggNOG; COG1061; Bacteria.
DR HOGENOM; CLU_020861_2_0_11; -.
DR OMA; HLKKQWA; -.
DR Proteomes; UP000000806; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW Reference proteome.
FT CHAIN 1..596
FT /note="Uncharacterized protein ML1624"
FT /id="PRO_0000104103"
FT DOMAIN 44..203
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT DOMAIN 285..432
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT REGION 420..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..527
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 596 AA; 65207 MW; 29AB6F40934C5E09 CRC64;
MTQSDHRHTR PSSYGGTVLT QRVSQATVED SRPLRGWQRR AMVKYLASQP RDFLAVATPG
SGKTTFALRV MTELLNSHAV EQVTVVVPTE HLKVQWTRAA ATHGLALDPK FSNTNPRTSP
EYHGVTMTYA QVAAHPTLHR VRTEGRRTLV IFDEIHHGGN AKAWGDAIRE AFSDATRRLA
LTGTPFRSDD KPIPFVTYAL DADGLMHSQA DHTYSYAEGL ADGVVRPVVF LVYSGQARWR
NSAGEEHAAR LGEPLSAEQT ARAWRTALDP SGEWMPAVIS AADQRLRQLR THVPDAGGMI
IASDQTAARA YANLLAQMTS ETPTLVLSDD PGSSARITEF AKNTSQWLIA VRMVSEGVDI
PRLSVGIYAT SASTPLFFAQ AIGRFVRSRH PGETASIFVP SVPNLLQLAS ELETQRNHVL
GKPHRESTDN PLGGNPATMT QTEQDDTEKY FTAIGADAEL DQIIFDGSSF GTATPAGSEE
EAYYLGIPGL LDADQMRALL HRRQNEQLQK RTAAQQASST PDRTSGAPAS VHGQLRELRR
ELNSLVSIAH HHTGKPHGWI HNELRRRCGG PPIAAATHDQ LKARIDAVRQ LNAEPS
