ID   Y1636_MYCTU             Reviewed;         146 AA.
AC   P9WFC9; L0T8U6; O06153; Q7D884;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 32.
DE   RecName: Full=Universal stress protein Rv1636;
DE            Short=USP Rv1636;
GN   OrderedLocusNames=Rv1636; ORFNames=TB15.3;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
RN   [3]
RP   X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 2-146.
RG   New York structural genomix research consortium (NYSGXRC);
RT   "Crystal structure of hypothetical protein Rv1636 from Mycobacterium
RT   tuberculosis H37Rv.";
RL   Submitted (FEB-2009) to the PDB data bank.
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000305}.
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DR   EMBL; AL123456; CCP44400.1; -; Genomic_DNA.
DR   PIR; B70560; B70560.
DR   RefSeq; NP_216152.1; NC_000962.3.
DR   RefSeq; WP_003408085.1; NZ_NVQJ01000016.1.
DR   PDB; 1TQ8; X-ray; 2.40 A; A/B/C/D/E/F=2-146.
DR   PDBsum; 1TQ8; -.
DR   AlphaFoldDB; P9WFC9; -.
DR   SMR; P9WFC9; -.
DR   STRING; 83332.Rv1636; -.
DR   PaxDb; P9WFC9; -.
DR   DNASU; 885473; -.
DR   GeneID; 45425605; -.
DR   GeneID; 885473; -.
DR   KEGG; mtu:Rv1636; -.
DR   TubercuList; Rv1636; -.
DR   eggNOG; COG0589; Bacteria.
DR   OMA; VHYSIEF; -.
DR   PhylomeDB; P9WFC9; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0009274; C:peptidoglycan-based cell wall; HDA:MTBBASE.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   GO; GO:0046677; P:response to antibiotic; IEP:MTBBASE.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006015; Universal_stress_UspA.
DR   InterPro; IPR006016; UspA.
DR   Pfam; PF00582; Usp; 1.
DR   PRINTS; PR01438; UNVRSLSTRESS.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome.
FT   CHAIN           1..146
FT                   /note="Universal stress protein Rv1636"
FT                   /id="PRO_0000396947"
FT   STRAND          6..10
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   HELIX           15..28
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   TURN            29..31
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   STRAND          32..39
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   HELIX           66..78
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   TURN            79..81
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   STRAND          84..90
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   HELIX           94..104
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   STRAND          108..113
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   HELIX           120..124
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   HELIX           128..135
FT                   /evidence="ECO:0007829|PDB:1TQ8"
FT   STRAND          139..143
FT                   /evidence="ECO:0007829|PDB:1TQ8"
SQ   SEQUENCE   146 AA;  15312 MW;  23FDE515DE3EF4ED CRC64;
     MSAYKTVVVG TDGSDSSMRA VDRAAQIAGA DAKLIIASAY LPQHEDARAA DILKDESYKV
     TGTAPIYEIL HDAKERAHNA GAKNVEERPI VGAPVDALVN LADEEKADLL VVGNVGLSTI
     AGRLLGSVPA NVSRRAKVDV LIVHTT