ID   Y1646_METS5             Reviewed;         348 AA.
AC   A4YH99;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=UPF0219 protein Msed_1646 {ECO:0000255|HAMAP-Rule:MF_01409};
GN   OrderedLocusNames=Msed_1646;
OS   Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS   / TH2).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Metallosphaera.
OX   NCBI_TaxID=399549;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2;
RX   PubMed=18083856; DOI=10.1128/aem.02019-07;
RA   Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT   "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT   archaeon Metallosphaera sedula provides insights into bioleaching-
RT   associated metabolism.";
RL   Appl. Environ. Microbiol. 74:682-692(2008).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. UPF0219 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01409}.
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DR   EMBL; CP000682; ABP95801.1; -; Genomic_DNA.
DR   RefSeq; WP_012021588.1; NC_009440.1.
DR   AlphaFoldDB; A4YH99; -.
DR   SMR; A4YH99; -.
DR   STRING; 399549.Msed_1646; -.
DR   EnsemblBacteria; ABP95801; ABP95801; Msed_1646.
DR   GeneID; 5104851; -.
DR   GeneID; 59457240; -.
DR   KEGG; mse:Msed_1646; -.
DR   eggNOG; arCOG01767; Archaea.
DR   HOGENOM; CLU_039592_7_0_2; -.
DR   OMA; YAKHKGK; -.
DR   Proteomes; UP000000242; Chromosome.
DR   GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 1.
DR   HAMAP; MF_01409; UPF0219; 1.
DR   InterPro; IPR013751; ACP_syn_III.
DR   InterPro; IPR013747; ACP_syn_III_C.
DR   InterPro; IPR004656; FabH-rel.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF08545; ACP_syn_III; 1.
DR   Pfam; PF08541; ACP_syn_III_C; 1.
DR   SUPFAM; SSF53901; SSF53901; 1.
DR   TIGRFAMs; TIGR00748; HMG_CoA_syn_Arc; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..348
FT                   /note="UPF0219 protein Msed_1646"
FT                   /id="PRO_1000184609"
SQ   SEQUENCE   348 AA;  37714 MW;  D012E17CCD688DD9 CRC64;
     MHTGIIGWGS YVPKYRIKVS DIASVWGKEE GVVKALGLTE KSVPAADEDS TTMAIEASRD
     ALTRAMIDPR EVEMALFGSE SKVYAVKSTS AILIDALGLS KFSLTADLEF ACRAASAGLR
     MAFSMVESGQ VSYSLVVGSD TAQSNPGDVL ELSSAAAAVA FVVGRAEEAS AVVEASTSYV
     TDTPDFWRRD GMPYPLHGEA FTGEPAYFAH IYEAVNRLLQ DTGLKVSDFD YFVFHQPNGK
     FPFQMAKKLG VPLEKVKQGM VSTLIGNPYN ASALLGFARV LDVAKPGQRV LVAPFGSGAG
     SDAYSFVITD KILERQKLAH TTDYYIQRKK LVDYASYAKT THKFKVYD