ID   Y1650_STAAW             Reviewed;         229 AA.
AC   Q8NW56;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 2.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=UPF0173 metal-dependent hydrolase MW1650 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=MW1650;
OS   Staphylococcus aureus (strain MW2).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=196620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MW2;
RX   PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA   Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA   Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT   "Genome and virulence determinants of high virulence community-acquired
RT   MRSA.";
RL   Lancet 359:1819-1827(2002).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB95515.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000033; BAB95515.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000777188.1; NC_003923.1.
DR   AlphaFoldDB; Q8NW56; -.
DR   SMR; Q8NW56; -.
DR   EnsemblBacteria; BAB95515; BAB95515; BAB95515.
DR   KEGG; sam:MW1650; -.
DR   HOGENOM; CLU_070010_4_1_9; -.
DR   Proteomes; UP000000418; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..229
FT                   /note="UPF0173 metal-dependent hydrolase MW1650"
FT                   /id="PRO_0000367219"
SQ   SEQUENCE   229 AA;  25251 MW;  C47ED323F2C7B246 CRC64;
     MKLSFHGQST IYLEGNNKKV IVDPFISNNP KCDLNIETVQ VDYIVLTHGH FDHFGDVVEL
     AKKTGATVIG SAEMADYLSS YHGVENVHGM NIGGKANFDF GSVKFVQAFH SSSFTHENGI
     PVYLGMPMGI VFEVEGKTIY HTGDTGLFSD MSLIAKRHPV DVCFVPIGDN FTMGIDDASY
     AINEFIKPKI SVPIHYDTFP LIEQDPQQFK DAVNVGDVQI LKPGESVQF