Y1652_ARATH
ID Y1652_ARATH Reviewed; 372 AA.
AC O80795; Q6NLP4;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Probable inactive receptor-like protein kinase At1g65250;
GN OrderedLocusNames=At1g65250; ORFNames=T8F5.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Carninci P., Hayashizaki Y.,
RA Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M.,
RA Shinozaki K., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC inactive.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. {ECO:0000305}.
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DR EMBL; AC004512; AAC27134.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34348.1; -; Genomic_DNA.
DR EMBL; BT012286; AAS76773.1; -; mRNA.
DR EMBL; AK221469; BAD94589.1; -; mRNA.
DR PIR; T02346; T02346.
DR RefSeq; NP_176704.1; NM_105198.3.
DR AlphaFoldDB; O80795; -.
DR SMR; O80795; -.
DR STRING; 3702.AT1G65250.1; -.
DR iPTMnet; O80795; -.
DR PaxDb; O80795; -.
DR PRIDE; O80795; -.
DR ProteomicsDB; 234340; -.
DR DNASU; 842832; -.
DR EnsemblPlants; AT1G65250.1; AT1G65250.1; AT1G65250.
DR GeneID; 842832; -.
DR Gramene; AT1G65250.1; AT1G65250.1; AT1G65250.
DR KEGG; ath:AT1G65250; -.
DR Araport; AT1G65250; -.
DR TAIR; locus:2206235; AT1G65250.
DR eggNOG; KOG1187; Eukaryota.
DR HOGENOM; CLU_000288_21_4_1; -.
DR InParanoid; O80795; -.
DR OMA; VIVYYDA; -.
DR OrthoDB; 778960at2759; -.
DR PhylomeDB; O80795; -.
DR PRO; PR:O80795; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; O80795; baseline and differential.
DR Genevisible; O80795; AT.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR045274; WAK-like.
DR PANTHER; PTHR27005; PTHR27005; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Nucleotide-binding; Phosphoprotein; Reference proteome.
FT CHAIN 1..372
FT /note="Probable inactive receptor-like protein kinase
FT At1g65250"
FT /id="PRO_0000401356"
FT DOMAIN 1..314
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT REGION 348..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 1..4
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 38
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT MOD_RES 128
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000250|UniProtKB:O48814"
FT MOD_RES 221
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000250|UniProtKB:O48814"
FT CONFLICT 237
FT /note="G -> V (in Ref. 3; AAS76773 and 4; BAD94589)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 372 AA; 42728 MW; 10EBBC02ECBFBECB CRC64;
MGWLRKKKKP KSDIASERGA KLLEELIECC DGKSNPIKFF SADEILKATN DFSDSNFVLR
LEVPFKWYSG KNENHPMILI KKDVGWWSGL RVDRLCRDIA VSSMVSGHKN FMKLVGCCLE
LDYPVMVYHS VKKHYKLEIS EQPWKKRMKI AEDIATALAY LHTAFPRPFV YRILSHWNIL
LDEDGVAKLT DFSHCVSIPE GETFVRVDRD VGLYSYFADN YVRSGLVSDK TDVFAFGIFM
GHRLLLGYEY YFEHYRGEEE ESEDGFDSLM KRHARNLLST LKEDRPMEEI ADSKMIEKMG
QISEQERCQM KAFLKLSLRC TGPSEEVPTM VEVAKELNKI QRSLFNDSSS LSSGQTQLDS
AQDISSTVVL SN
