ID   Y1653_METJA             Reviewed;         385 AA.
AC   Q59047;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Putative ribosomal RNA large subunit methyltransferase MJ1653;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MJ1653;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmI family.
CC       {ECO:0000305}.
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DR   EMBL; L77117; AAB99674.1; -; Genomic_DNA.
DR   PIR; C64506; C64506.
DR   RefSeq; WP_010871177.1; NC_000909.1.
DR   AlphaFoldDB; Q59047; -.
DR   SMR; Q59047; -.
DR   STRING; 243232.MJ_1653; -.
DR   EnsemblBacteria; AAB99674; AAB99674; MJ_1653.
DR   GeneID; 1452562; -.
DR   KEGG; mja:MJ_1653; -.
DR   eggNOG; arCOG00032; Archaea.
DR   HOGENOM; CLU_014042_0_0_2; -.
DR   InParanoid; Q59047; -.
DR   OMA; DCFCHTG; -.
DR   OrthoDB; 59984at2157; -.
DR   PhylomeDB; Q59047; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.130.10; -; 1.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR041532; RlmI_PUA-like.
DR   InterPro; IPR019614; SAM-dep_methyl-trfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF10672; Methyltrans_SAM; 1.
DR   Pfam; PF17785; PUA_3; 1.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Methyltransferase; Reference proteome; RNA-binding;
KW   rRNA processing; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..385
FT                   /note="Putative ribosomal RNA large subunit
FT                   methyltransferase MJ1653"
FT                   /id="PRO_0000213171"
FT   DOMAIN          2..81
FT                   /note="PUA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00161"
SQ   SEQUENCE   385 AA;  43763 MW;  27EC604EC4A435ED CRC64;
     MTTKLYVDFG GYSAIEKGNL IIPRDNILNK EDFDSIEIGE VVDIYSKRGK FLGRGFKNPK
     EVRIMTLRKE DLDENYIREK IIKANEYRLK LGFKDTYRMV YTQSDWLNGL VIDKYNDIAT
     VQIFNYGIEK MKDVVVETLL DLGIDSIYEK SSGRNRKRAG LPEVEGILAG EKTETIIQEG
     EAKFKVTFDG QKTGFFLDQR ENRLELEKFI KEGDRVLDIC CYTGGFSVHA AIRGAEVVGV
     DLSKKALKLA EENMELNNIP KDRYEFIEGN AFKVMEEFIE DGEKFDVVIL DPPAFAQSKK
     ALKSAIKGYH MLNRFGAKLA DRLLVTCSCS QPLEPDAFKA LVIDACLKAK KWAKIIKYGS
     QSPDHPITSK GTEYLKCLFL SVEEI