ID   Y165_METJA              Reviewed;         256 AA.
AC   Q57629;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Uncharacterized protein MJ0165;
GN   OrderedLocusNames=MJ0165;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; L77117; AAB98147.1; -; Genomic_DNA.
DR   PIR; F64320; F64320.
DR   RefSeq; WP_010869660.1; NC_000909.1.
DR   AlphaFoldDB; Q57629; -.
DR   SMR; Q57629; -.
DR   STRING; 243232.MJ_0165; -.
DR   EnsemblBacteria; AAB98147; AAB98147; MJ_0165.
DR   GeneID; 1451012; -.
DR   KEGG; mja:MJ_0165; -.
DR   eggNOG; arCOG02465; Archaea.
DR   HOGENOM; CLU_065705_0_0_2; -.
DR   InParanoid; Q57629; -.
DR   OMA; EVIWGPG; -.
DR   OrthoDB; 73714at2157; -.
DR   PhylomeDB; Q57629; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR   InterPro; IPR039476; P2CMN_synthase_LarB.
DR   InterPro; IPR000031; PurE_dom.
DR   PANTHER; PTHR43064; PTHR43064; 1.
DR   Pfam; PF00731; AIRC; 1.
DR   SMART; SM01001; AIRC; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..256
FT                   /note="Uncharacterized protein MJ0165"
FT                   /id="PRO_0000106727"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   256 AA;  28107 MW;  AB9DE5847D62D928 CRC64;
     MGKNLRDLLL AFKNGDISLD EIEKQIKLNY YEEIEERLKL DINRQFRTGV PEVVYGKGKD
     IDEIIKATLK LVEKNGIALA TKIEDIEKLS DEIRKWNLKN YDIKINKKAK TLIIKNKNYE
     VKKIGKVGIL TAGTSDIPVA EEAKDTLEIM GVEAITAYDV GIAGIHRLFP ALKRMIEEDV
     CCIIVVAGME GALPSVIASM VDIPVIGVPT STSYGIKITP LLTMLHSCSP GIAVVNIDNG
     FGAGVFAGLI AKIMHK