Y1668_ARATH
ID Y1668_ARATH Reviewed; 685 AA.
AC Q9C9N5; Q0WPB5;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Probable inactive leucine-rich repeat receptor-like protein kinase At1g66830;
DE Flags: Precursor;
GN OrderedLocusNames=At1g66830; ORFNames=F4N21.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=20064227; DOI=10.1186/1471-2164-11-19;
RA Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.;
RT "Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-
RT like protein kinase genes in Arabidopsis thaliana.";
RL BMC Genomics 11:19-19(2010).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I
CC membrane protein {ECO:0000250}.
CC -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC inactive.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
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DR EMBL; AC013288; AAG60082.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34560.1; -; Genomic_DNA.
DR EMBL; FJ708670; ACN59265.1; -; mRNA.
DR EMBL; AK229161; BAF01034.1; -; mRNA.
DR RefSeq; NP_176855.1; NM_105354.3.
DR AlphaFoldDB; Q9C9N5; -.
DR SMR; Q9C9N5; -.
DR BioGRID; 28222; 37.
DR IntAct; Q9C9N5; 35.
DR STRING; 3702.AT1G66830.1; -.
DR iPTMnet; Q9C9N5; -.
DR PaxDb; Q9C9N5; -.
DR PRIDE; Q9C9N5; -.
DR ProteomicsDB; 243036; -.
DR EnsemblPlants; AT1G66830.1; AT1G66830.1; AT1G66830.
DR GeneID; 843001; -.
DR Gramene; AT1G66830.1; AT1G66830.1; AT1G66830.
DR KEGG; ath:AT1G66830; -.
DR Araport; AT1G66830; -.
DR TAIR; locus:2033379; AT1G66830.
DR eggNOG; ENOG502SJN0; Eukaryota.
DR HOGENOM; CLU_000288_92_6_1; -.
DR InParanoid; Q9C9N5; -.
DR OMA; DQISPME; -.
DR OrthoDB; 826997at2759; -.
DR PhylomeDB; Q9C9N5; -.
DR PRO; PR:Q9C9N5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C9N5; baseline and differential.
DR Genevisible; Q9C9N5; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; Leucine-rich repeat; Membrane; Phosphoprotein;
KW Receptor; Reference proteome; Repeat; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..685
FT /note="Probable inactive leucine-rich repeat receptor-like
FT protein kinase At1g66830"
FT /id="PRO_0000401343"
FT TOPO_DOM 22..305
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 327..685
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REPEAT 65..89
FT /note="LRR 1"
FT REPEAT 90..113
FT /note="LRR 2"
FT REPEAT 115..136
FT /note="LRR 3"
FT REPEAT 137..161
FT /note="LRR 4"
FT REPEAT 162..185
FT /note="LRR 5"
FT REPEAT 186..210
FT /note="LRR 6"
FT REPEAT 212..234
FT /note="LRR 7"
FT REPEAT 235..260
FT /note="LRR 8"
FT DOMAIN 397..682
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT MOD_RES 399
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q94F62"
FT MOD_RES 480
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9LSI9"
FT MOD_RES 590
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q94AG2"
FT CARBOHYD 38
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 48
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 151
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 193
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 247
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 264
FT /note="N -> D (in Ref. 4; BAF01034)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 685 AA; 76025 MW; B071D58DE8726C35 CRC64;
MSQLFLILCF ILTHFFAIAT SLNDQGLALL SFKQSIQNQS DSVFTNWNSS DSNPCSWQGV
TCNYDMRVVS IRLPNKRLSG SLDPSIGSLL SLRHINLRDN DFQGKLPVEL FGLKGLQSLV
LSGNSFSGFV PEEIGSLKSL MTLDLSENSF NGSISLSLIP CKKLKTLVLS KNSFSGDLPT
GLGSNLVHLR TLNLSFNRLT GTIPEDVGSL ENLKGTLDLS HNFFSGMIPT SLGNLPELLY
VDLSYNNLSG PIPKFNVLLN AGPNAFQGNP FLCGLPIKIS CSTRNTQVVP SQLYTRRANH
HSRLCIILTA TGGTVAGIIF LASLFIYYLR KASARANKDQ NNRTCHINEK LKKTTKPEFL
CFKTGNSESE TLDENKNQQV FMPMDPEIEF DLDQLLKASA FLLGKSRIGL VYKVVLENGL
MLAVRRLEDK GWLRLKEFLA DVEAMAKIKH PNVLNLKACC WSPEEKLLIY DYIPNGDLGS
AIQGRPGSVS CKQLTWTVRL KILRGIAKGL TYIHEFSPKR YVHGHINTSN ILLGPNLEPK
VSGFGLGRIV DTSSDIRSDQ ISPMETSSPI LSRESYYQAP EAASKMTKPS QKWDVYSFGL
VILEMVTGKS PVSSEMDLVM WVESASERNK PAWYVLDPVL ARDRDLEDSM VQVIKIGLAC
VQKNPDKRPH MRSVLESFEK LVTSI
