Y1676_DICDI
ID Y1676_DICDI Reviewed; 533 AA.
AC Q75JD4; Q55AN1;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=SH3 and F-BAR domain-containing protein DDB_G0271676;
GN ORFNames=DDB_G0271676;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000006; EAL71528.1; -; Genomic_DNA.
DR RefSeq; XP_645491.1; XM_640399.1.
DR AlphaFoldDB; Q75JD4; -.
DR SMR; Q75JD4; -.
DR STRING; 44689.DDB0266842; -.
DR PaxDb; Q75JD4; -.
DR EnsemblProtists; EAL71528; EAL71528; DDB_G0271676.
DR GeneID; 8618119; -.
DR KEGG; ddi:DDB_G0271676; -.
DR dictyBase; DDB_G0271676; nlp.
DR eggNOG; KOG3565; Eukaryota.
DR eggNOG; KOG4225; Eukaryota.
DR HOGENOM; CLU_511356_0_0_1; -.
DR InParanoid; Q75JD4; -.
DR OMA; WAAIMTE; -.
DR PhylomeDB; Q75JD4; -.
DR Reactome; R-DDI-8856828; Clathrin-mediated endocytosis.
DR PRO; PR:Q75JD4; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IDA:dictyBase.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0031982; C:vesicle; IDA:dictyBase.
DR GO; GO:0008017; F:microtubule binding; IDA:dictyBase.
DR GO; GO:0035091; F:phosphatidylinositol binding; IBA:GO_Central.
DR GO; GO:0030041; P:actin filament polymerization; IGI:dictyBase.
DR GO; GO:0043327; P:chemotaxis to cAMP; IGI:dictyBase.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IBA:GO_Central.
DR GO; GO:0016050; P:vesicle organization; IGI:dictyBase.
DR Gene3D; 1.20.1270.60; -; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF103657; SSF103657; 1.
DR SUPFAM; SSF50044; SSF50044; 2.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Coiled coil; Reference proteome; Repeat; SH3 domain.
FT CHAIN 1..533
FT /note="SH3 and F-BAR domain-containing protein
FT DDB_G0271676"
FT /id="PRO_0000384438"
FT DOMAIN 5..258
FT /note="F-BAR"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01077"
FT DOMAIN 406..468
FT /note="SH3 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00192"
FT DOMAIN 476..533
FT /note="SH3 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00192"
FT REGION 126..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 301..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 76..186
FT /evidence="ECO:0000255"
FT COMPBIAS 301..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 533 AA; 60358 MW; 3EF7E888B6317FB0 CRC64;
MSAQRQFSED LWDKFESVVK KVDNGKIFTQ QLSKFLSKQQ QIESAYAKSL VKLCKDKSFA
PEVEMGTLRD SFQCYREQLE LIGALHEEFS NRLEKLVTIG IDGYLEESRK QRKALIANGE
KCTKDLKTAE SNESKAKQNY EKLKRKQEEA NEDLSKQPPG AKEQKARKTL ESATKAADKG
DNEYRESVKC LQQNQQKFYH EEMPRILDDL QRFEVERIDK SKDWLMEVIT QNELVPPAVI
IHNENIKKGI ESIDRERDLQ NYILVTMSGA QKPPEAQYEP YQSGGGFAIV NSSSNSNLNI
SRKSGELNGG GSIQNGASII SSPQQPQYQN IDHQTPPQPN IIIQQHQQSN NNNNTNNNSN
VMTTPPPPQP QPQQQQLPQP TQLNNPPQPP ISLSKNDSSN SINSNSNGEI VRALYDYNAT
EENEISFKAN ALIKVVLRDE SGWWQGMVIG ESDRIGVFPS NFISDSSDSS KKRVDVAGRK
CKVLYDYRTD CEGELNIKEG EILTIEYEDE GWFFGSNESN VSARFPSNYV QVI
