ID   Y1686_ARATH             Reviewed;         474 AA.
AC   Q9FZ45;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Uncharacterized membrane protein At1g16860;
GN   OrderedLocusNames=At1g16860; ORFNames=F6I1.14;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-45 AND SER-169, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19376835; DOI=10.1104/pp.109.138677;
RA   Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA   Grossmann J., Gruissem W., Baginsky S.;
RT   "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT   chloroplast kinase substrates and phosphorylation networks.";
RL   Plant Physiol. 150:889-903(2009).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AC051629; AAF99847.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE29511.1; -; Genomic_DNA.
DR   EMBL; AY050887; AAK92824.1; -; mRNA.
DR   EMBL; AY117261; AAM51336.1; -; mRNA.
DR   EMBL; BT000665; AAN31812.1; -; mRNA.
DR   PIR; H86303; H86303.
DR   RefSeq; NP_564009.1; NM_101547.4.
DR   AlphaFoldDB; Q9FZ45; -.
DR   BioGRID; 23497; 2.
DR   IntAct; Q9FZ45; 2.
DR   STRING; 3702.AT1G16860.1; -.
DR   iPTMnet; Q9FZ45; -.
DR   PaxDb; Q9FZ45; -.
DR   PRIDE; Q9FZ45; -.
DR   ProteomicsDB; 234341; -.
DR   EnsemblPlants; AT1G16860.1; AT1G16860.1; AT1G16860.
DR   GeneID; 838257; -.
DR   Gramene; AT1G16860.1; AT1G16860.1; AT1G16860.
DR   KEGG; ath:AT1G16860; -.
DR   Araport; AT1G16860; -.
DR   TAIR; locus:2015646; AT1G16860.
DR   eggNOG; ENOG502QRIM; Eukaryota.
DR   HOGENOM; CLU_041384_0_0_1; -.
DR   InParanoid; Q9FZ45; -.
DR   OMA; FIWNICW; -.
DR   OrthoDB; 719651at2759; -.
DR   PhylomeDB; Q9FZ45; -.
DR   PRO; PR:Q9FZ45; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9FZ45; baseline and differential.
DR   Genevisible; Q9FZ45; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR   GO; GO:2001007; P:negative regulation of cellulose biosynthetic process; IGI:TAIR.
DR   InterPro; IPR040339; At1g16860-like.
DR   PANTHER; PTHR33709; PTHR33709; 1.
PE   1: Evidence at protein level;
KW   Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..474
FT                   /note="Uncharacterized membrane protein At1g16860"
FT                   /id="PRO_0000302045"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..137
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        96..112
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         45
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:19376835"
FT   MOD_RES         169
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:19376835"
SQ   SEQUENCE   474 AA;  50583 MW;  560A1B082D815C1C CRC64;
     MGSRYPSHQL SNGLFVSGRP EQPKERAPTM SAVAMPYTGG DIKRSGELGK MFDIPADGTK
     SRKSGPIPGA PSRSGSFAGT AQSGPGAPMA TGRMSGSLAS AGSVSMKKTN SGPLSKHGEP
     LKKSSGPQSG GVTRQNSGSI PILPATGLIT SGPITSGPLN SSGAPRKVSG PLDSSGLMKS
     HMPTVVHNQA VTTLGPEDDF SCLKSFPKPV LWLVVLIFIM GFLAGGFILG AVHNPILLVV
     VAILFTVVAA LFIWNICWGR RGITDFIARY PDADLRTAKN GQHVKVTGVV TCGNVPLESS
     FHRVPRCVYT STCLYEYRGW GSKPANSSHR HFTWGLRSSE RHVVDFYISD FQSGLRALVK
     TGSGAKVTPL VDDSVVIDFK QGSEQVSPDF VRWLGKKNLT SDDRIMRLKE GYIKEGSTVS
     VIGVVQRNDN VLMIVPSSEP LAAGWQWRRC TFPTSLEGIV LRCEDSSNVD AIPV