ID   Y1686_STRPN             Reviewed;         367 AA.
AC   Q54728;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   26-SEP-2001, sequence version 2.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Uncharacterized oxidoreductase SP_1686;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=SP_1686;
OS   Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=170187;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-334 / TIGR4;
RX   PubMed=11463916; DOI=10.1126/science.1061217;
RA   Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D.,
RA   Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J.,
RA   Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D.,
RA   Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D.,
RA   Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L.,
RA   McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K.,
RA   Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A.,
RA   Morrison D.A., Hollingshead S.K., Fraser C.M.;
RT   "Complete genome sequence of a virulent isolate of Streptococcus
RT   pneumoniae.";
RL   Science 293:498-506(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-347.
RC   STRAIN=Serotype 6;
RX   PubMed=8759848; DOI=10.1128/jb.178.16.4854-4860.1996;
RA   Berry A.M., Lock R.A., Paton J.C.;
RT   "Cloning and characterization of nanB, a second Streptococcus pneumoniae
RT   neuraminidase gene, and purification of the NanB enzyme from recombinant
RT   Escherichia coli.";
RL   J. Bacteriol. 178:4854-4860(1996).
CC   -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE005672; AAK75765.1; -; Genomic_DNA.
DR   EMBL; U43526; AAC44397.1; -; Genomic_DNA.
DR   PIR; D95196; D95196.
DR   RefSeq; WP_000241734.1; NZ_AKVY01000001.1.
DR   AlphaFoldDB; Q54728; -.
DR   SMR; Q54728; -.
DR   STRING; 170187.SP_1686; -.
DR   EnsemblBacteria; AAK75765; AAK75765; SP_1686.
DR   KEGG; spn:SP_1686; -.
DR   eggNOG; COG0673; Bacteria.
DR   OMA; VEYAAWS; -.
DR   PhylomeDB; Q54728; -.
DR   BioCyc; SPNE170187:G1FZB-1707-MON; -.
DR   Proteomes; UP000000585; Chromosome.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..367
FT                   /note="Uncharacterized oxidoreductase SP_1686"
FT                   /id="PRO_0000091782"
FT   CONFLICT        9
FT                   /note="T -> A (in Ref. 2; AAC44397)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        156
FT                   /note="P -> L (in Ref. 2; AAC44397)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   367 AA;  41095 MW;  DE1D666A7752325D CRC64;
     MVKYGVVGTG YFGAELARYM QKNDGAEITL LYDPDNAEAI AEELGAKVAS SLDELVSSDE
     VDCVIVATPN NLHKEPVIKA AQHGKNVFCE KPIALSYQDC REMVDACKEN NVTFMAGHIM
     NFFNGVHHAK ELINQGVIGD VLYCHTARNG WEEQQPSVSW KKIREKSGGH LYHHIHELDC
     VQFLMGGMPE TVTMTGGNVA HEGEHFGDED DMIFVNMEFS NKRFALLEWG SAYRWGEHYV
     LIQGSKGAIR LDLFNCKGTL KLDGQESYFL IHESQEEDDD RTRIYHSTEM DGAIAYGKPG
     KRTPLWLSSV IDKEMRYLHE IMEGAPVSEE FAKLLTGEAA LEAIATADAC TQSMFEDRKV
     KLSEIVK