ID   Y168_MYCGI              Reviewed;         246 AA.
AC   A4T2U3;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mflv_0168;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mflv_0168;
OS   Mycolicibacterium gilvum (strain PYR-GCK) (Mycobacterium gilvum (strain
OS   PYR-GCK)).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=350054;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PYR-GCK;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.;
RT   "Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000656; ABP42663.1; -; Genomic_DNA.
DR   RefSeq; WP_011891170.1; NC_009338.1.
DR   AlphaFoldDB; A4T2U3; -.
DR   SMR; A4T2U3; -.
DR   STRING; 350054.Mflv_0168; -.
DR   EnsemblBacteria; ABP42663; ABP42663; Mflv_0168.
DR   KEGG; mgi:Mflv_0168; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; WDITEGV; -.
DR   OrthoDB; 847145at2; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..246
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mflv_0168"
FT                   /id="PRO_0000361154"
FT   BINDING         112
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         141..142
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   246 AA;  26548 MW;  1501A53F6E0B8528 CRC64;
     MTILDSPGAP DTGIDALALG TAVARVRETS SDQPLFTDRY SQMLVDAAGP MEPDQAALAV
     PGYVAARTKW FDDFFLAASA AGLAQIVLLS PGLDTRAWRL PWLNDTVIFE VDRPRTLAFK
     QQTLTRAGVT PTATYVPVPV DLGDDWPRAL TAAGFSHGEP TAWAAEGLYA DLPEAEQDNL
     LERIDLYSAR GSRIAMDVDA DGPDVVCWLC ARHWEMGSTD APDVMARYHR DAAGAPSGVF
     VEGRKL