ID   Y1690_HAEIN             Reviewed;         457 AA.
AC   P45320;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Uncharacterized sodium-dependent transporter HI_1690;
GN   OrderedLocusNames=HI_1690;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Putative sodium-dependent transporter.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC       2.A.22) family. {ECO:0000305}.
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DR   EMBL; L42023; AAC23336.1; -; Genomic_DNA.
DR   PIR; H64136; H64136.
DR   RefSeq; NP_439832.1; NC_000907.1.
DR   RefSeq; WP_005694179.1; NC_000907.1.
DR   AlphaFoldDB; P45320; -.
DR   SMR; P45320; -.
DR   STRING; 71421.HI_1690; -.
DR   EnsemblBacteria; AAC23336; AAC23336; HI_1690.
DR   KEGG; hin:HI_1690; -.
DR   PATRIC; fig|71421.8.peg.1769; -.
DR   eggNOG; COG0733; Bacteria.
DR   HOGENOM; CLU_006855_3_4_6; -.
DR   OMA; GMATFIF; -.
DR   PhylomeDB; P45320; -.
DR   BioCyc; HINF71421:G1GJ1-1706-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   InterPro; IPR000175; Na/ntran_symport.
DR   InterPro; IPR037272; SNS_sf.
DR   Pfam; PF00209; SNF; 2.
DR   PRINTS; PR00176; NANEUSMPORT.
DR   SUPFAM; SSF161070; SSF161070; 1.
DR   PROSITE; PS00610; NA_NEUROTRAN_SYMP_1; 1.
DR   PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Symport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..457
FT                   /note="Uncharacterized sodium-dependent transporter
FT                   HI_1690"
FT                   /id="PRO_0000214819"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        188..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        228..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        294..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        316..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        355..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        396..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        433..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   457 AA;  50756 MW;  00C1897F3A3E112A CRC64;
     MTTNNKQRQT WSSRLTYVMT VAGATVGFGA TWRFPYLVGE NGGGAYVLLF CIAMIVIGIP
     MILVENVIGR RLRVNSIDAF GDKILDKGKG ISKYWKILGY MGLLGAFGIM AYYMVLGGWV
     ISYIISLISG TLDISTPITK DIAKNFYDLH IGNSPYEIIF YTLLFVIVNY IILAKGIIGG
     IERSVKYLMP LLFIFLIGMV IRNVTLPGAM EGITFYLKPD FSKITPQLFI FVLGQVFFAL
     SLGFGVLITL SSYLNKEENL IHTAVITGFT NTIIAVLAGF MIFPSLFTFG IEPNAGPTLV
     FQSLPIVFSH LWAGKFFAII FFGLLLIAAL TTSITIYEVI ITALQEKLRM CRGKAIVLTL
     SGIFLLGNIP AILGDNLWKN VTIFGKSIFD FYDYASGNIL FMLTALGCAI FVGFVLKDEA
     KKELSSTKYS TFIKIWFNYV KFVVPLIILV IFISNLF