Y1691_LEGPH
ID Y1691_LEGPH Reviewed; 464 AA.
AC P37034; Q5ZUV1;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 2.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Uncharacterized transporter lpg1691;
GN OrderedLocusNames=lpg1691;
OS Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS 33152 / DSM 7513).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=272624;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513;
RX PubMed=15448271; DOI=10.1126/science.1099776;
RA Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA Chou I.-C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA Russo J.J.;
RT "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL Science 305:1966-1968(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-57.
RX PubMed=8366052; DOI=10.1128/jb.175.17.5666-5676.1993;
RA Mengaud J.M., Horwitz M.A.;
RT "The major iron-containing protein of Legionella pneumophila is an
RT aconitase homologous with the human iron-responsive element-binding
RT protein.";
RL J. Bacteriol. 175:5666-5676(1993).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. {ECO:0000305}.
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DR EMBL; AE017354; AAU27771.1; -; Genomic_DNA.
DR EMBL; L22081; AAA25296.1; -; Genomic_DNA.
DR PIR; C48642; C48642.
DR RefSeq; WP_010947418.1; NC_002942.5.
DR RefSeq; YP_095718.1; NC_002942.5.
DR AlphaFoldDB; P37034; -.
DR SMR; P37034; -.
DR STRING; 272624.lpg1691; -.
DR PaxDb; P37034; -.
DR EnsemblBacteria; AAU27771; AAU27771; lpg1691.
DR GeneID; 66490823; -.
DR KEGG; lpn:lpg1691; -.
DR PATRIC; fig|272624.6.peg.1772; -.
DR eggNOG; COG0531; Bacteria.
DR HOGENOM; CLU_020854_4_2_6; -.
DR OMA; AWNFSGF; -.
DR Proteomes; UP000000609; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002293; AA/rel_permease1.
DR Pfam; PF13520; AA_permease_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..464
FT /note="Uncharacterized transporter lpg1691"
FT /id="PRO_0000054223"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 121..141
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 153..173
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 359..379
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 401..421
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 432..452
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 464 AA; 50778 MW; AB835A4CCC9CF06D CRC64;
MNHSKKVLNV FSLVMINVIA VDSLRTLPIS AKLGFSLVFY YIFAALTFFI PVALVAAELA
TAYPNTGGIY VWVREAFGRR AGFITIWLQW IYNVVWYPTM LAFIAATLSY LIAPHLGNNK
FYLLGTALTL FWVFTFLNCF GMKLSSIVSI IGASIGTLLP MIVIIVLGAV WIFQDRPVAV
NYPTTWLPDF SSLGNLSLFS AVLFGLIGME MSAVHAEEVK NPQRDYPKAL FYSALLIIST
LSLGSLAIVI VVPNDSLSVV SGLVDAYAIF FNSYNMPWMT SVIAVLIILG GLSGVSAWII
GPTKGLLVSA RDGSLPALFS RVNKYGSPVA ILLTQGVIFT VLSTVFILLD SINAAYWVLS
DLSAQMALLV YIMMFAAAIK LRYSKPEQPR GYTIPGGNLV MSLISGIGII CCIAAMIVGF
IPPSQIPIKN VFLFECFLIG GLILFVFIPW LFAKKHDEQL CSEE