ID   Y1693_STAA1             Reviewed;         229 AA.
AC   A7X3D5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=UPF0173 metal-dependent hydrolase SAHV_1693 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=SAHV_1693;
OS   Staphylococcus aureus (strain Mu3 / ATCC 700698).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=418127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu3 / ATCC 700698;
RX   PubMed=17954695; DOI=10.1128/aac.00534-07;
RA   Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.;
RT   "Mutated response regulator graR is responsible for phenotypic conversion
RT   of Staphylococcus aureus from heterogeneous vancomycin-intermediate
RT   resistance to vancomycin-intermediate resistance.";
RL   Antimicrob. Agents Chemother. 52:45-53(2008).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; AP009324; BAF78576.1; -; Genomic_DNA.
DR   RefSeq; WP_000777188.1; NZ_CTYB01000008.1.
DR   AlphaFoldDB; A7X3D5; -.
DR   SMR; A7X3D5; -.
DR   KEGG; saw:SAHV_1693; -.
DR   HOGENOM; CLU_070010_4_1_9; -.
DR   OMA; WHGHSTW; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..229
FT                   /note="UPF0173 metal-dependent hydrolase SAHV_1693"
FT                   /id="PRO_1000013509"
SQ   SEQUENCE   229 AA;  25251 MW;  C47ED323F2C7B246 CRC64;
     MKLSFHGQST IYLEGNNKKV IVDPFISNNP KCDLNIETVQ VDYIVLTHGH FDHFGDVVEL
     AKKTGATVIG SAEMADYLSS YHGVENVHGM NIGGKANFDF GSVKFVQAFH SSSFTHENGI
     PVYLGMPMGI VFEVEGKTIY HTGDTGLFSD MSLIAKRHPV DVCFVPIGDN FTMGIDDASY
     AINEFIKPKI SVPIHYDTFP LIEQDPQQFK DAVNVGDVQI LKPGESVQF