ID   Y1714_MYCTO             Reviewed;         270 AA.
AC   P9WGQ2; L0T923; O53927; Q7D837;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 38.
DE   RecName: Full=Uncharacterized oxidoreductase MT1753.1;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=MT1753.1;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46025.1; -; Genomic_DNA.
DR   PIR; B70817; B70817.
DR   RefSeq; WP_003408444.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WGQ2; -.
DR   SMR; P9WGQ2; -.
DR   EnsemblBacteria; AAK46025; AAK46025; MT1753.1.
DR   KEGG; mtc:MT1753.1; -.
DR   PATRIC; fig|83331.31.peg.1883; -.
DR   HOGENOM; CLU_010194_1_1_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..270
FT                   /note="Uncharacterized oxidoreductase MT1753.1"
FT                   /id="PRO_0000428322"
FT   ACT_SITE        171
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         30..55
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         157
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   270 AA;  27986 MW;  33BAA2B0E04EA3AB CRC64;
     MEEMALAQQV PNLGLARFSV QDKSILITGA TGSLGRVAAR ALADAGARLT LAGGNSAGLA
     ELVNGAGIDD AAVVTCRPDS LADAQQMVEA ALGRYGRLDG VLVASGSNHV APITEMAVED
     FDAVMDANVR GAWLVCRAAG RVLLEQGQGG SVVLVSSVRG GLGNAAGYSA YCPSKAGTDL
     LAKTLAAEWG GHGIRVNALA PTVFRSAVTE WMFTDDPKGR ATREAMLARI PLRRFAEPED
     FVGALIYLLS DASSFYTGQV MYLDGGYTAC