ID   Y1724_PYRFU             Reviewed;         131 AA.
AC   Q8U077;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=UPF0292 protein PF1724 {ECO:0000255|HAMAP-Rule:MF_01095};
GN   OrderedLocusNames=PF1724;
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX   PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01095};
CC       Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_01095};
CC   -!- SIMILARITY: Belongs to the UPF0292 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01095}.
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DR   EMBL; AE009950; AAL81848.1; -; Genomic_DNA.
DR   RefSeq; WP_011012870.1; NZ_CP023154.1.
DR   AlphaFoldDB; Q8U077; -.
DR   SMR; Q8U077; -.
DR   STRING; 186497.PF1724; -.
DR   EnsemblBacteria; AAL81848; AAL81848; PF1724.
DR   GeneID; 41713555; -.
DR   KEGG; pfu:PF1724; -.
DR   PATRIC; fig|186497.12.peg.1792; -.
DR   eggNOG; arCOG01486; Archaea.
DR   HOGENOM; CLU_140789_3_0_2; -.
DR   OMA; VMILTDF; -.
DR   OrthoDB; 99443at2157; -.
DR   PhylomeDB; Q8U077; -.
DR   Proteomes; UP000001013; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01027; TOPRIM_RNase_M5_like; 1.
DR   HAMAP; MF_01095; UPF0292; 1.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   InterPro; IPR034141; TOPRIM_RNase_M5-like.
DR   InterPro; IPR022972; UPF0292.
DR   Pfam; PF01751; Toprim; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   3: Inferred from homology;
KW   Magnesium; Metal-binding; Reference proteome.
FT   CHAIN           1..131
FT                   /note="UPF0292 protein PF1724"
FT                   /id="PRO_0000143955"
FT   DOMAIN          20..103
FT                   /note="Toprim"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         26
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="1"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         69
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="1"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         69
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         71
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
SQ   SEQUENCE   131 AA;  15354 MW;  2AE31171A563CD6D CRC64;
     MYPENYEKFE KIIERLREFK GVIIVEGKRD EDSLRKLGVQ TEILRLSRSS LADVALLASE
     HEEVMILTDF DETGEKLAKR LYDLLVGLTK VDMETRRELQ FIASKDAKGI EDLYDLWESL
     RLRFWAPKEG D