ID   Y1725_METS5             Reviewed;         299 AA.
AC   A4YHH8;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Putative HTH-type transcriptional regulatory protein Msed_1725 {ECO:0000255|HAMAP-Rule:MF_00584};
GN   OrderedLocusNames=Msed_1725;
OS   Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS   / TH2).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Metallosphaera.
OX   NCBI_TaxID=399549;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2;
RX   PubMed=18083856; DOI=10.1128/aem.02019-07;
RA   Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT   "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT   archaeon Metallosphaera sedula provides insights into bioleaching-
RT   associated metabolism.";
RL   Appl. Environ. Microbiol. 74:682-692(2008).
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DR   EMBL; CP000682; ABP95880.1; -; Genomic_DNA.
DR   RefSeq; WP_012021667.1; NC_009440.1.
DR   AlphaFoldDB; A4YHH8; -.
DR   SMR; A4YHH8; -.
DR   STRING; 399549.Msed_1725; -.
DR   EnsemblBacteria; ABP95880; ABP95880; Msed_1725.
DR   GeneID; 5105088; -.
DR   GeneID; 59457157; -.
DR   KEGG; mse:Msed_1725; -.
DR   eggNOG; arCOG04152; Archaea.
DR   HOGENOM; CLU_075726_1_0_2; -.
DR   OMA; PGVVYFR; -.
DR   Proteomes; UP000000242; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   HAMAP; MF_00584; HTH_type_cro_C1; 1.
DR   InterPro; IPR020886; Arc_TR_HTH.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..299
FT                   /note="Putative HTH-type transcriptional regulatory protein
FT                   Msed_1725"
FT                   /id="PRO_1000146938"
FT   DOMAIN          125..180
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
FT   DNA_BIND        136..155
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
SQ   SEQUENCE   299 AA;  33322 MW;  62CB4D21DB9F10CE CRC64;
     MIPGMLDEVL DVLEREGISY TLIEYPEKNR KSIDIIARGK QRRFVIKISN DRPSKEETRD
     LKNFSAVVGS MPVMVTDDTE EDIAIGKDNV IGLSVEGLAK ALRGEKIFIY RTRGGIFIKI
     RSDVLRRKRT EMNYSMGDLS KILGVTRKTI YDYENGESDV SIEVAEKLID LFGDEVIGDV
     CDDALPKLEP DSQPTDTISS RIAKNLTDAG FASAPIRFTA VDVVASRGLK KVLVTVEPKN
     QDQLEKKLRE ASKIANELMS ELVIVVKSAS MAKRLDKDGF KILTSESIDS LSDEINRSD