ID   Y1728_HAEIN             Reviewed;         397 AA.
AC   O05087;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Uncharacterized membrane protein HI_1728;
GN   OrderedLocusNames=HI_1728;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the NRAMP family. {ECO:0000305}.
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DR   EMBL; L42023; AAC23374.1; -; Genomic_DNA.
DR   PIR; G64138; G64138.
DR   RefSeq; NP_439869.1; NC_000907.1.
DR   RefSeq; WP_005694214.1; NC_000907.1.
DR   AlphaFoldDB; O05087; -.
DR   SMR; O05087; -.
DR   STRING; 71421.HI_1728; -.
DR   EnsemblBacteria; AAC23374; AAC23374; HI_1728.
DR   KEGG; hin:HI_1728; -.
DR   PATRIC; fig|71421.8.peg.1807; -.
DR   eggNOG; COG1914; Bacteria.
DR   HOGENOM; CLU_055818_0_0_6; -.
DR   OMA; QTNVWRI; -.
DR   PhylomeDB; O05087; -.
DR   BioCyc; HINF71421:G1GJ1-1743-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015086; F:cadmium ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IBA:GO_Central.
DR   InterPro; IPR001046; NRAMP_fam.
DR   PANTHER; PTHR11706; PTHR11706; 1.
DR   Pfam; PF01566; Nramp; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..397
FT                   /note="Uncharacterized membrane protein HI_1728"
FT                   /id="PRO_0000099776"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        310..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        365..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   397 AA;  41962 MW;  1868D392018BD492 CRC64;
     MASITHRRNA VLGAAFLMAT SAIGPGFLTQ TATFTNTLLA SFGFVILLSI LLDIGAQLNI
     WRIVIVSGKR AQDISNAVFP KAGYFLAALI VMGGLAFNIG NVGGAGLGLN SIFGIAPEMG
     AVISGIIAIL IFLRKEAGLL MDRFAQLMGF IMVVLTFYVM FKTEPPVVEA AYHSFIPEQI
     DPIAIVTLVG GTVGGYITFA GAHRLLDAGI QGEKAMAEVS RSSVSAILIA STMRVVLFLA
     VLGVVSKGVS LNPKNPAETP FEYVAGNFGQ VLFGVVIWAA SVTSVIGAAY TSVSFLTTLC
     PTIERNRNRW IIAFIVISTV VLVTVGKPAA VLVFVGTLNG LILPIALALI LLAAYRSDIV
     GTYKHPVFLA FSGWFVVIIM AILSGKTIIS YISSFFS