ID   CAPSD_SSRV1             Reviewed;         134 AA.
AC   A0A6M3VXD3; A0A7M4DUE5;
DT   29-SEP-2021, integrated into UniProtKB/Swiss-Prot.
DT   07-OCT-2020, sequence version 1.
DT   03-AUG-2022, entry version 7.
DE   RecName: Full=Major capsid protein {ECO:0000303|PubMed:32759221};
DE   AltName: Full=Gp11 {ECO:0000303|PubMed:32759221};
GN   ORFNames=SSRV1_gp11 {ECO:0000312|EMBL:QJF12287.1};
OS   Saccharolobus solfataricus rod-shaped virus 1 (SSRV1).
OC   Viruses; Adnaviria; Zilligvirae; Taleaviricota; Tokiviricetes;
OC   Ligamenvirales; Rudiviridae; Hoswirudivirus; Hoswirudivirus SSRV1.
OX   NCBI_TaxID=2730619;
OH   NCBI_TaxID=2287; Saccharolobus solfataricus (Sulfolobus solfataricus).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=149 {ECO:0000305};
RX   PubMed=32322010; DOI=10.1038/s41396-020-0653-z;
RA   Baquero D.P., Contursi P., Piochi M., Bartolucci S., Liu Y.,
RA   Cvirkaite-Krupovic V., Prangishvili D., Krupovic M.;
RT   "New virus isolates from Italian hydrothermal environments underscore the
RT   biogeographic pattern in archaeal virus communities.";
RL   ISME J. 14:1821-1833(2020).
RN   [2]
RP   STRUCTURE BY ELECTRON MICROSCOPY (2.80 ANGSTROMS), SUBUNIT, FUNCTION,
RP   SUBCELLULAR LOCATION, AND DOMAIN.
RC   STRAIN=149 {ECO:0000305};
RX   PubMed=32759221; DOI=10.1073/pnas.2011125117;
RA   Wang F., Baquero D.P., Beltran L.C., Su Z., Osinski T., Zheng W.,
RA   Prangishvili D., Krupovic M., Egelman E.H.;
RT   "Structures of filamentous viruses infecting hyperthermophilic archaea
RT   explain DNA stabilization in extreme environments.";
RL   Proc. Natl. Acad. Sci. U.S.A. 117:19643-19652(2020).
CC   -!- FUNCTION: Self-assembles to form a helical, filamentous nucleocapsid.
CC       The capsid proteins wrap around the DNA and maintain it in an A-form by
CC       non-specific desolvation and specific coordination of the DNA phosphate
CC       groups by positively charged residues. This certainly protects the
CC       viral DNA under conditions such as the extreme desiccation of its host.
CC       {ECO:0000269|PubMed:32759221}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000269|PubMed:32759221}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:32759221}.
CC   -!- DOMAIN: The N-terminus projects into a DNA groove.
CC       {ECO:0000269|PubMed:32759221}.
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DR   EMBL; MN876841; QJF12287.1; -; Genomic_DNA.
DR   PDB; 6WQ0; EM; 2.80 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/a/b/c/d/e/f/g/h/i/j/k/l/m/n/o/p/q/r/s/t/u/v/w=1-134.
DR   PDBsum; 6WQ0; -.
DR   SMR; A0A6M3VXD3; -.
DR   Proteomes; UP000503449; Genome.
DR   GO; GO:0019029; C:helical viral capsid; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   InterPro; IPR022014; Sulfobus_virus_coat_C.
DR   Pfam; PF12193; Sulf_coat_C; 1.
PE   1: Evidence at protein level;
KW   3D-structure; DNA-binding; Reference proteome; Virion.
FT   CHAIN           1..134
FT                   /note="Major capsid protein"
FT                   /id="PRO_0000453805"
SQ   SEQUENCE   134 AA;  14195 MW;  F86A1AC11DAA15C9 CRC64;
     MAKGRTPRSF SQRYGKWNAK FTAFSNPTVA STILTNVAPI AQGNFQTNVP KFTSVNEQVS
     AVLTQYGVTG PSRAIYQGYG LKVARALNRI GAGPALTNMV AGLKAYYVSA YGANPEILDA
     VTNIILGSPT GYVS