CAPSD_TASV1
ID CAPSD_TASV1 Reviewed; 671 AA.
AC Q9JH68;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 23-FEB-2022, entry version 51.
DE RecName: Full=Capsid polyprotein VP90;
GN ORFNames=ORF2;
OS Turkey astrovirus 1 (TAstV-1).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Stelpaviricetes;
OC Stellavirales; Astroviridae; Avastrovirus.
OX NCBI_TaxID=364370;
OH NCBI_TaxID=9103; Meleagris gallopavo (Wild turkey).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=12573498; DOI=10.1016/s0168-1702(02)00269-1;
RA Jonassen C.M., Jonassen T.O., Sveen T.M., Grinde B.;
RT "Complete genomic sequences of astroviruses from sheep and turkey:
RT comparison with related viruses.";
RL Virus Res. 91:195-201(2003).
CC -!- FUNCTION: Capsid polyprotein VP90: self-assembles to form an
CC icosahedral T=3 capsid. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- PTM: Specific enzymatic cleavages in vivo yield mature protein(s). VP90
CC undergoes a cascade of proteolytic cleavages presumably mediated by
CC host caspases and extracellular proteases (By similarity).
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the astroviridae capsid polyprotein family.
CC {ECO:0000305}.
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DR EMBL; Y15936; CAB95007.1; -; Genomic_RNA.
DR SMR; Q9JH68; -.
DR Proteomes; UP000000676; Genome.
DR GO; GO:0039615; C:T=1 icosahedral viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0039573; P:suppression by virus of host complement activation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.20; -; 1.
DR InterPro; IPR004337; Capsid_astroviral.
DR InterPro; IPR029053; Viral_coat.
DR Pfam; PF03115; Astro_capsid_N; 1.
PE 3: Inferred from homology;
KW Capsid protein; Host-virus interaction;
KW Inhibition of host complement factors by virus; Reference proteome;
KW T=1 icosahedral capsid protein; Viral immunoevasion; Virion.
FT CHAIN 1..671
FT /note="Capsid polyprotein VP90"
FT /id="PRO_0000320242"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..36
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 671 AA; 72514 MW; 8B4DAA430BE4DB30 CRC64;
MSAPAGKAGP KAQKKCKVVT QKTKTVPKKT KQQKPRKVRL QKVERQVKTL KAKTRGPKIS
DTFSTVVTVG RIIGNNDDSL TRQLKVFVNP LLMKNQDSGS TSSPLSIRAS QYGLWKIAKL
HVYFTPLAGS ANVIGTVSFA SLEQESGVAT AESPDTIKAK YHAEVPIGSR FVWKVPPRML
TGPREGWWNM DSGDDPTNSV GPSISFWTYL KTILALSTAT TTSYLGSLFL IEIRCTYLFS
NYAPKPNLAI MVNEKITTTQ PVTLTNLSDG SLVMTTTDTR LCALLDNDRG PRGPNAQTNG
PGEKFWAVST LVVDTVAASI GPWGWLLKGG WWVIRKIFGA ANTTSTYAIY ASVEDAAKDS
RIYQPVSGTQ TLAAGDVYVT QLTQPNVNEA GSTSLGFSPP TPPAPTGSYL PLPQAAGVPG
IPPQYTFSDG QYTAATTWSG TQLYLTGVPA TKTVSGSNEM FGVENNTMSR ANIDRVQIYD
FTTTGIIFLG GQNRSGGAIH TAKTLIVALK TATTKAPWLA ADATGTNWAM PSWVGFPVPG
AGDHFLQMQN STDRTTHTTP VGVYFLVAYG ATNKLVAFWA APTDVQAEPT SLMTLYNVDA
GRAPITAGLN FTTAMTEYSD DDDDAESDIS SLFAPDEVDW KFKIEASSSR HLEEELQFWK
SKATQLMLEK N